Safety of Thioguanine in Pediatric Inflammatory Bowel Disease: A Multi-Center Case Series

Thioguanine (TG) has been shown as a safe alternative in adults with inflammatory bowel disease (IBD) who did not tolerate conventional thiopurines [azathioprine (AZA)/mercaptopurine]. However, data in pediatric IBD are scarce. Therefore, we aimed to assess the safety of TG as maintenance therapy. A...

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Veröffentlicht in:	Journal of pediatric gastroenterology and nutrition 2022-12, Vol.75 (6), p.e111-e115
Hauptverfasser:	Bayoumy, Ahmed B., Jagt, Jasmijn Z., van Wering, Herbert M., de Ridder, Lissy, Hummel, Thalia, Wolters, Victorien M., Stapelbroek, Janneke, Benninga, Marc A., Mulder, Chris J.J., de Boer, Nanne K.H., de Meij, Tim G.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Azathioprine - therapeutic use Child Chronic Disease Cohort Studies Humans Immunosuppressive Agents - adverse effects Inflammatory Bowel Diseases - drug therapy Mercaptopurine - adverse effects Original : Gastroenterology: Inflammatory Bowel Disease Pancreatitis - chemically induced Pancreatitis - drug therapy Retrospective Studies Thioguanine - adverse effects
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