IgA Vasculitis With Adalimumab Therapy for Hidradenitis Suppurativa: A Case Report and Review of Literature
Immunoglobulin A (IgA) vasculitis is a systemic vasculitis characterized by inflammation of the small vessels, with cutaneous, musculoskeletal, gastrointestinal, and renal involvement, usually seen in pediatric populations. Hidradenitis suppurativa is a chronic inflammatory disorder of the skin, whi...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2022-10, Vol.14 (10) |
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| creator | Alsulami, Sarah Alotaibi, Rakan M Alotaibi, Faisal F Almatrafi, Faisal B Filmban, Doaa M Alneefia, Sultan Alahmed, AhmedHusam Hafiz, Waleed A |
| description | Immunoglobulin A (IgA) vasculitis is a systemic vasculitis characterized by inflammation of the small vessels, with cutaneous, musculoskeletal, gastrointestinal, and renal involvement, usually seen in pediatric populations. Hidradenitis suppurativa is a chronic inflammatory disorder of the skin, which can be treated by tumor necrosis factor-α (TNFα) inhibitor therapy. TNFα inhibitor therapy is used as an important milestone in the treatment of various rheumatological and autoimmune disorders. Unexpected adverse effects might occur. However, they are usually mild and do not warrant treatment withdrawal. We present a case of IgA vasculitis complicating adalimumab therapy for hidradenitis suppurativa. We also review and discuss similar cases reported in the literature. |
| doi_str_mv | 10.7759/cureus.30122 |
| format | Article |
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Hidradenitis suppurativa is a chronic inflammatory disorder of the skin, which can be treated by tumor necrosis factor-α (TNFα) inhibitor therapy. TNFα inhibitor therapy is used as an important milestone in the treatment of various rheumatological and autoimmune disorders. Unexpected adverse effects might occur. However, they are usually mild and do not warrant treatment withdrawal. We present a case of IgA vasculitis complicating adalimumab therapy for hidradenitis suppurativa. 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| subjects | Abdomen Allergy/Immunology Arthritis Case reports Creatinine Crohns disease Dermatology Emergency medical care Inflammatory bowel disease Laboratories Monoclonal antibodies Pain Patients Pediatrics Purpura Rheumatology Skin Steroids TNF inhibitors White people |
| title | IgA Vasculitis With Adalimumab Therapy for Hidradenitis Suppurativa: A Case Report and Review of Literature |
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