Evaluating data integrity in ribosome footprinting datasets through modelled polysome profiles

The assessment of transcriptome-wide ribosome binding to mRNAs is useful for studying the dynamic regulation of protein synthesis. Two methods frequently applied in eukaryotic cells that operate at different levels of resolution are polysome profiling, which reveals the distribution of ribosome load...

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Veröffentlicht in:	Nucleic acids research 2022-10, Vol.50 (19), p.e112-e112
Hauptverfasser:	Hedayioglu, Fabio, Mead, Emma J, O'Connor, Patrick B F, Skiotys, Matas, Sansom, Owen J, Mallucci, Giovanna R, Willis, Anne E, Baranov, Pavel V, Smales, C Mark, von der Haar, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Methods Online Polyribosomes - metabolism Protein Biosynthesis Ribosomes - genetics Ribosomes - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transcriptome
Online-Zugang:	Volltext
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