CXCR1 participates in bone cancer pain induced by Walker 256 breast cancer cells in female rats

Bone cancer pain (BCP) is a clinically intractable mixed pain, involving inflammation and neuropathic pain, and its mechanisms remain unclear. CXC chemokine receptor 1 (CXCR1, IL-8RA) and 2 (CXCR2, IL-8RB) are high-affinity receptors for interleukin 8 (IL8). According to previous studies, CXCR2 play...

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Veröffentlicht in:	Molecular pain 2022-10, Vol.18, p.17448069221135743-17448069221135743
Hauptverfasser:	Xu, Chengfei, Zhao, Baoxia, Xu, Longsheng, Wang, Yahui, Liu, Beibei, Xu, Miao, He, Qiuli, Ni, Chaobo, Fu, Jie, Kong, Min, Lin, Xuewu, Ni, Huadong, Yao, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytes Bone cancer Breast cancer Chemokine receptors Chemokines CXC chemokines CXCR2 protein Dorsal horn IL-1β Inflammasomes Interleukin 8 Janus kinase 2 Mechanical properties Neuralgia Pain Pain perception Signal transduction siRNA Stat3 protein
Online-Zugang:	Volltext
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