Ventrolateral Periaqueductal Gray Astrocytes Regulate Nociceptive Sensation and Emotional Motivation in Diabetic Neuropathic Pain

Diabetic neuropathic pain (DNP) is a diabetes complication experienced by many patients. Ventrolateral periaqueductal gray (vlPAG) neurons are essential mediators of the descending pain modulation system, yet the role of vlPAG astrocytes in DNP remains unclear. The present study applied a multidimen...

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Veröffentlicht in:	The Journal of neuroscience 2022-10, Vol.42 (43), p.8184-8199
Hauptverfasser:	Yang, Lan, Lu, Jingshan, Guo, Jianpeng, Chen, Jian, Xiong, Fangfang, Wang, Xinyao, Chen, Li, Yu, Changxi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Astrocytes Aversion Designer Drugs Diabetes Diabetes Mellitus Diabetic Neuropathies Diabetic neuropathy Male Males Motivation Neuralgia Nociception - physiology Pain Pain perception Periaqueductal Gray - physiology Periaqueductal gray area Rats Sensation
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