18F-PI-2620 Tau PET Improves the Imaging Diagnosis of Progressive Supranuclear Palsy

Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy movement disorder that can be imaged by the 18F-labeled tau PET tracer 2-(2-([18F]fluoro)pyridin-4-yl)-9H-pyrrolo[2,3-b:4,5-c′]dipyridine (18F-PI-2620). The in vivo diagnosis is currently established on clinical grounds and supported by mi...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2022-11, Vol.63 (11), p.1754-1760
Hauptverfasser:	Messerschmidt, Konstantin, Barthel, Henryk, Brendel, Matthias, Scherlach, Cordula, Hoffmann, Karl-Titus, Rauchmann, Boris-Stephan, Rullmann, Michael, Marek, Kenneth, Villemagne, Victor L, Rumpf, Jost-Julian, Saur, Dorothee, Schroeter, Matthias L, Schildan, Andreas, Patt, Marianne, Beyer, Leonie, Song, Mengmeng, Palleis, Carla, Katzdobler, Sabrina, Fietzek, Urban M, Respondek, Gesine, Scheifele, Maximilian, Nitschmann, Alexander, Zach, Christian, Barret, Olivier, Madonia, Jennifer, Russell, David, Stephens, Andrew W, Koglin, Norman, Roeber, Sigrun, Herms, Jochen, Bötzel, Kai, Bartenstein, Peter, Levin, Johannes, Seibyl, John P, Höglinger, Günter, Classen, Joseph, Sabri, Osama
Format:	Artikel
Sprache:	eng
Schlagworte:	Atrophy Clinical Investigation Clinical trials Diagnosis Evaluation Fluorine isotopes Globus pallidus Magnetic resonance imaging Medical diagnosis Medical imaging Mesencephalon Neurodegenerative diseases Paralysis Patients Phenotypes Pons Positron emission Progressive supranuclear palsy Sensitivity Subgroups Tau protein Visual discrimination
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