Human SFI1 and Centrin form a complex critical for centriole architecture and ciliogenesis

Over the course of evolution, the centrosome function has been conserved in most eukaryotes, but its core architecture has evolved differently in some clades, with the presence of centrioles in humans and a spindle pole body (SPB) in yeast. Similarly, the composition of these two core elements has d...

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Veröffentlicht in:	The EMBO journal 2022-11, Vol.41 (21), p.e112107-n/a
Hauptverfasser:	Laporte, Marine H, Bouhlel, Imène B, Bertiaux, Eloïse, Morrison, Ciaran G, Giroud, Alexia, Borgers, Susanne, Azimzadeh, Juliette, Bornens, Michel, Guichard, Paul, Paoletti, Anne, Hamel, Virginie
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium-Binding Proteins - metabolism Cell Cycle Proteins - metabolism Centrioles Centrioles - metabolism centrosome ciliogenesis Depletion Divergence EMBO05 EMBO06 EMBO40 Eukaryotes Evolution Evolutionary conservation expansion microscopy human cells Humans Life Sciences Proteins Repressor Proteins - metabolism Reproduction (copying) Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - metabolism Spindle Pole Bodies - metabolism Yeast Yeasts
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