IgM+ and IgM− memory B cells represent heterogeneous populations capable of producing class-switched antibodies and germinal center B cells upon re-challenge with P. yoelii
Memory B cells (MBCs) are essential for maintaining long-term humoral immunity to infectious organisms, including Plasmodium . MBCs are a heterogeneous population whose function can be dictated by isotype or expression of particular surface proteins. Here, aided by antigen-specific B-cell tetramers,...
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Veröffentlicht in: | Journal of leukocyte biology 2022-06, Vol.112 (5), p.1115-1135 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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