An integrative analysis of Qingfei Paidu Decoction for its anti-HCoV-229E mechanism in cold and damp environment based on the pharmacokinetics, metabolomics and molecular docking technology

The novel coronavirus pneumonia (COVID-19) has spread rapidly around the world. As a member against the epidemic, Qingfei Paidu Decoction (QFPDD) has been approved for the treatment of COVID-19 in China. However, its antiviral mechanism was still largely unclear. An integrated strategy was used to e...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2023-01, Vol.108, p.154527, Article 154527
Hauptverfasser:	Zhang, Yan, Gu, Xinru, Zhou, Yanyan, Si, Nan, Gao, Wenya, Sun, Bo, Sun, Jing, Li, Tao, Wang, Linna, Wei, Xiaolu, Guo, Shanshan, Cui, Xiaolan, Bian, Baolin, Wang, Hongjie, Wang, Liang, Zhao, Haiyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Coronavirus 229E, Human COVID-19 Drug Treatment Drugs, Chinese Herbal - chemistry HCoV-229E Humans Metabolomics Molecular Docking Simulation Network pharmacology Original Pharmacokinetics Qingfei Paidu Decoction Technology
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