Boswellia serrata Extract, 5-Loxin®, Prevents Joint Pain and Cartilage Degeneration in a Rat Model of Osteoarthritis through Inhibition of Inflammatory Responses and Restoration of Matrix Homeostasis

Osteoarthritis (OA) is a chronic, progressive joint disease associated with pain, functional impairment, and diminished quality of life in affected individuals. At a societal level, it also has a high economic burden. Boswellia serrata has been reported to have potent anti-inflammatory, antiarthriti...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2022-10, Vol.2022, p.1-11
Hauptverfasser:	Shin, Mi-Rae, Kim, Hwa-Young, Choi, Hwang-Yong, Park, Kyoung Sik, Choi, Hak Joo, Roh, Seong-Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggrecan Analgesics Arachidonate 5-lipoxygenase Arthritis Boswellia serrata Cartilage Cartilage diseases Computed tomography Cyclooxygenase-2 Cytokines Degeneration Enzymes Extracellular matrix Glycosaminoglycans Homeostasis Inflammation Joint diseases Lipoxygenase Matrix metalloproteinase Oral administration Osteoarthritis Pain Polymerase chain reaction Prostaglandin endoperoxide synthase Proteins Quality of life Rodents Tumor necrosis factor-TNF
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