Transcriptional dynamics of pluripotent stem cell-derived endothelial cell differentiation revealed by single-cell RNA sequencing

Abstract Aims Pluripotent stem cell-derived endothelial cell products possess therapeutic potential in ischaemic vascular disease. However, the factors that drive endothelial differentiation from pluripotency and cellular specification are largely unknown. The aims of this study were to use single-c...

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Veröffentlicht in:	European heart journal 2020-03, Vol.41 (9), p.1024-1036
Hauptverfasser:	McCracken, Ian R, Taylor, Richard S, Kok, Fatma O, de la Cuesta, Fernando, Dobie, Ross, Henderson, Beth E P, Mountford, Joanne C, Caudrillier, Axelle, Henderson, Neil C, Ponting, Chris P, Baker, Andrew H
Format:	Artikel
Sprache:	eng
Schlagworte:	Basic Science Cell Differentiation Embryonic Stem Cells Endothelial Cells Humans Pluripotent Stem Cells Sequence Analysis, RNA
Online-Zugang:	Volltext
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