Identification of a novel signaling complex containing host chemokine receptor CXCR4, Interleukin-10 receptor, and human cytomegalovirus US27

Human cytomegalovirus (HCMV) is a widespread herpesvirus that establishes latency in myeloid cells and persists by manipulating immune signaling. Chemokine receptor CXCR4 and its ligand CXCL12 regulate movement of myeloid progenitors into bone marrow and out into peripheral tissues. HCMV amplifies C...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2020-09, Vol.548, p.49-58
Hauptverfasser:	Tu, Carolyn C., O'Connor, Christine M., Spencer, Juliet V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemokine cmvIL-10 CXCL12 CXCR4 Cytokine Cytomegalovirus HCMV IL-10R Interleukin-10 Proximity ligation assay US27
Online-Zugang:	Volltext
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