Virus-Associated Nephropathies: A Narrative Review
While most viral infections cause mild symptoms and a spontaneous favorable resolution, some can lead to severe or protracted manifestations, specifically in immunocompromised hosts. Kidney injuries related to viral infections may have multiple causes related to the infection severity, drug toxicity...
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| Veröffentlicht in: | International journal of molecular sciences 2022-10, Vol.23 (19), p.12014 |
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| container_title | International journal of molecular sciences |
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| creator | Masset, Christophe Le Turnier, Paul Bressollette-Bodin, Céline Renaudin, Karine Raffi, François Dantal, Jacques |
| description | While most viral infections cause mild symptoms and a spontaneous favorable resolution, some can lead to severe or protracted manifestations, specifically in immunocompromised hosts. Kidney injuries related to viral infections may have multiple causes related to the infection severity, drug toxicity or direct or indirect viral-associated nephropathy. We review here the described virus-associated nephropathies in order to guide diagnosis strategies and treatments in cases of acute kidney injury (AKI) occurring concomitantly with a viral infection. The occurrence of virus-associated nephropathy depends on multiple factors: the local epidemiology of the virus, its ability to infect renal cells and the patient’s underlying immune response, which varies with the state of immunosuppression. Clear comprehension of pathophysiological mechanisms associated with a summary of described direct and indirect injuries should help physicians to diagnose and treat viral associated nephropathies. |
| doi_str_mv | 10.3390/ijms231912014 |
| format | Article |
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| subjects | Acquired immune deficiency syndrome AIDS Apoptosis Asymptomatic Bacterial infections Cell growth Drug therapy Epidemiology Heparan sulfate Hepatitis A Hepatitis B Hepatitis C HIV Human immunodeficiency virus Immune response Immune system Immunocompromised hosts Immunosuppression Infections Injuries Kidney diseases Kidney transplants Kidneys Life Sciences Nephropathy Review Toxicity Viral infections Viruses |
| title | Virus-Associated Nephropathies: A Narrative Review |
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