Quantification of Plasma 8-Isoprostane by High-Performance Liquid Chromatography with Tandem Mass Spectrometry in a Case-Control Study of Lung Cancer

8-iso-prostaglandin F2α is a biomarker of lipid peroxidation, and one of the most commonly used measures of oxidative stress. It is an established biomarker of lung cancer risk. It is commonly measured by enzyme-linked immunosorbent assay. Given its importance, we developed a stable isotope dilution...

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Veröffentlicht in:	International journal of environmental research and public health 2022-09, Vol.19 (19), p.12488
Hauptverfasser:	Ma, Lin, Sun, Dongxiao, Xiu, Guangli, Lazarus, Philip, Vachani, Anil, Penning, Trevor M, Whitehead, Alexander S, Muscat, Joshua E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Asthma Biomarkers Cancer screening Case-Control Studies Chromatography Chromatography, High Pressure Liquid - methods Chromatography, Liquid Chronic obstructive pulmonary disease Dilution Dinoprost - analogs & derivatives Early Detection of Cancer Enzyme-linked immunosorbent assay Health risks High performance liquid chromatography Humans Isotopes Lipid peroxidation Lipids Liquid chromatography Lung cancer Lung diseases Lung Neoplasms - diagnosis Lung nodules Mass spectrometry Mass spectroscopy Nodules Obstructive lung disease Oxidative Stress Peroxidation Plasma Prostaglandin F2a Pulmonary Disease, Chronic Obstructive Scientific imaging Smoking Stable isotopes Tandem Mass Spectrometry - methods Urine Variance analysis
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