Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial
The presence of latent myofascial trigger points (MTrPs) in the gluteus medius is one of the possible causes of non-specific low back pain. Dry needling (DN) and ischemic compression (IC) techniques may be useful for the treatment of these MTrPs. For this study, 80 participants were randomly divided...
Gespeichert in:
Veröffentlicht in: | International journal of environmental research and public health 2022-09, Vol.19 (19), p.12468 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | 19 |
container_start_page | 12468 |
container_title | International journal of environmental research and public health |
container_volume | 19 |
creator | Álvarez, Sara Delgado Velázquez Saornil, Jorge Sánchez Milá, Zacarías Jaén Crespo, Gonzalo Campón Chekroun, Angélica Barragán Casas, José Manuel Frutos Llanes, Raúl Rodríguez Sanz, David |
description | The presence of latent myofascial trigger points (MTrPs) in the gluteus medius is one of the possible causes of non-specific low back pain. Dry needling (DN) and ischemic compression (IC) techniques may be useful for the treatment of these MTrPs.
For this study, 80 participants were randomly divided into two groups: the dry needling group, who received a single session of DN to the gluteus medius muscle plus hyperalgesia (
= 40), and the IC group, who received a single session of IC to the gluteus medius muscle plus hyperalgesia (
= 40). Pain intensity, the pressure pain threshold (PPT), range of motion (ROM), and quality of life were assessed at baseline, immediately after treatment, after 48 h, and one week after treatment.
Statistically significant differences were shown between the two groups immediately after the intervention, showing a decrease in PPT (
< 0.05) in the DN group and an increase in PPT in the IC group. These values increased more and were better maintained at 48 h and after one week of treatment in the DN group than in the IC group. Quality of life improved in both groups, with greater improvement in the DN group than in the IC group.
IC could be more advisable than DN with respect to UDP and pain intensity in the most hyperalgesic latent MTrPs of the gluteus medius muscle in subjects with non-specific low back pain, immediately after treatment. DN may be more effective than IC in terms of PPT, pain intensity, and quality of life in treating latent plus hyperalgesic gluteus medius muscle MTrPs in subjects with non-specific low back pain after 48 h and after one week of treatment. |
doi_str_mv | 10.3390/ijerph191912468 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9564974</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2725203902</sourcerecordid><originalsourceid>FETCH-LOGICAL-c421t-75ba17fa18ad1589405deea9d9f78f929bb11c01aeae5538d8cfc369b8044b603</originalsourceid><addsrcrecordid>eNpdksFO3DAQhqOqVaGUM7fKUi-9pNix48Q9VKJbSpG2FMFyjhxnvPE2sYPtgOhD9RnrFRRR5MNY9jf_zK-ZLDsg-COlAh-aDfipJyKdgvH6RbZLOMc545i8fHLfyd6EsMGY1oyL19kO5QUlFa92sz_HWoOK5gYshICcRl_9HToD6AZj10jaDp0G1cNoFFp5s16DR-fO2IgWbpx8yjHOImNR7AGdDHOEOaAf0JkU0uu5jAZsDOjWxB6dOZtfTqCMTmpLd4u-SPUrMcZ-QkfoIhVzo_kNHbrsnY_5CvyIFqkPo-SwrS6Ht9krLYcA-w9xL7v6drxafM-XP09OF0fLXLGCxLwqW0kqLUktO1LWguGyA5CiE7qqtShE2xKiMJEgoSxp3dVKK8pFW2PGWo7pXvb5Xnea2xE6lTx4OTSTN6P0d42Tpvn_x5q-WbubRpSciYolgQ8PAt5dzxBiM5qgYBikBTeHpqiKssBphEVC3z9DN272NtnbUqxgVY1pog7vKeVdCB70YzMEN9tdaJ7tQsp499TDI_9v-PQvGx-zmA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2724247803</pqid></control><display><type>article</type><title>Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Álvarez, Sara Delgado ; Velázquez Saornil, Jorge ; Sánchez Milá, Zacarías ; Jaén Crespo, Gonzalo ; Campón Chekroun, Angélica ; Barragán Casas, José Manuel ; Frutos Llanes, Raúl ; Rodríguez Sanz, David</creator><creatorcontrib>Álvarez, Sara Delgado ; Velázquez Saornil, Jorge ; Sánchez Milá, Zacarías ; Jaén Crespo, Gonzalo ; Campón Chekroun, Angélica ; Barragán Casas, José Manuel ; Frutos Llanes, Raúl ; Rodríguez Sanz, David</creatorcontrib><description>The presence of latent myofascial trigger points (MTrPs) in the gluteus medius is one of the possible causes of non-specific low back pain. Dry needling (DN) and ischemic compression (IC) techniques may be useful for the treatment of these MTrPs.
For this study, 80 participants were randomly divided into two groups: the dry needling group, who received a single session of DN to the gluteus medius muscle plus hyperalgesia (
= 40), and the IC group, who received a single session of IC to the gluteus medius muscle plus hyperalgesia (
= 40). Pain intensity, the pressure pain threshold (PPT), range of motion (ROM), and quality of life were assessed at baseline, immediately after treatment, after 48 h, and one week after treatment.
Statistically significant differences were shown between the two groups immediately after the intervention, showing a decrease in PPT (
< 0.05) in the DN group and an increase in PPT in the IC group. These values increased more and were better maintained at 48 h and after one week of treatment in the DN group than in the IC group. Quality of life improved in both groups, with greater improvement in the DN group than in the IC group.
IC could be more advisable than DN with respect to UDP and pain intensity in the most hyperalgesic latent MTrPs of the gluteus medius muscle in subjects with non-specific low back pain, immediately after treatment. DN may be more effective than IC in terms of PPT, pain intensity, and quality of life in treating latent plus hyperalgesic gluteus medius muscle MTrPs in subjects with non-specific low back pain after 48 h and after one week of treatment.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph191912468</identifier><identifier>PMID: 36231767</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Back pain ; Clinical trials ; Compression ; Dry Needling ; Humans ; Hyperalgesia ; Informed consent ; Low back pain ; Low Back Pain - therapy ; Manipulative therapy ; Muscles ; Nervous system ; Pain ; Pain perception ; Pathology ; Patients ; Quality assessment ; Quality of Life ; Range of motion ; Statistical analysis ; Therapeutic applications ; Trigger Points ; Uridine Diphosphate</subject><ispartof>International journal of environmental research and public health, 2022-09, Vol.19 (19), p.12468</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2022 by the authors. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-75ba17fa18ad1589405deea9d9f78f929bb11c01aeae5538d8cfc369b8044b603</citedby><cites>FETCH-LOGICAL-c421t-75ba17fa18ad1589405deea9d9f78f929bb11c01aeae5538d8cfc369b8044b603</cites><orcidid>0000-0002-3629-6590 ; 0000-0002-4129-2084 ; 0000-0003-2608-2019</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564974/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564974/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36231767$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Álvarez, Sara Delgado</creatorcontrib><creatorcontrib>Velázquez Saornil, Jorge</creatorcontrib><creatorcontrib>Sánchez Milá, Zacarías</creatorcontrib><creatorcontrib>Jaén Crespo, Gonzalo</creatorcontrib><creatorcontrib>Campón Chekroun, Angélica</creatorcontrib><creatorcontrib>Barragán Casas, José Manuel</creatorcontrib><creatorcontrib>Frutos Llanes, Raúl</creatorcontrib><creatorcontrib>Rodríguez Sanz, David</creatorcontrib><title>Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>The presence of latent myofascial trigger points (MTrPs) in the gluteus medius is one of the possible causes of non-specific low back pain. Dry needling (DN) and ischemic compression (IC) techniques may be useful for the treatment of these MTrPs.
For this study, 80 participants were randomly divided into two groups: the dry needling group, who received a single session of DN to the gluteus medius muscle plus hyperalgesia (
= 40), and the IC group, who received a single session of IC to the gluteus medius muscle plus hyperalgesia (
= 40). Pain intensity, the pressure pain threshold (PPT), range of motion (ROM), and quality of life were assessed at baseline, immediately after treatment, after 48 h, and one week after treatment.
Statistically significant differences were shown between the two groups immediately after the intervention, showing a decrease in PPT (
< 0.05) in the DN group and an increase in PPT in the IC group. These values increased more and were better maintained at 48 h and after one week of treatment in the DN group than in the IC group. Quality of life improved in both groups, with greater improvement in the DN group than in the IC group.
IC could be more advisable than DN with respect to UDP and pain intensity in the most hyperalgesic latent MTrPs of the gluteus medius muscle in subjects with non-specific low back pain, immediately after treatment. DN may be more effective than IC in terms of PPT, pain intensity, and quality of life in treating latent plus hyperalgesic gluteus medius muscle MTrPs in subjects with non-specific low back pain after 48 h and after one week of treatment.</description><subject>Back pain</subject><subject>Clinical trials</subject><subject>Compression</subject><subject>Dry Needling</subject><subject>Humans</subject><subject>Hyperalgesia</subject><subject>Informed consent</subject><subject>Low back pain</subject><subject>Low Back Pain - therapy</subject><subject>Manipulative therapy</subject><subject>Muscles</subject><subject>Nervous system</subject><subject>Pain</subject><subject>Pain perception</subject><subject>Pathology</subject><subject>Patients</subject><subject>Quality assessment</subject><subject>Quality of Life</subject><subject>Range of motion</subject><subject>Statistical analysis</subject><subject>Therapeutic applications</subject><subject>Trigger Points</subject><subject>Uridine Diphosphate</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdksFO3DAQhqOqVaGUM7fKUi-9pNix48Q9VKJbSpG2FMFyjhxnvPE2sYPtgOhD9RnrFRRR5MNY9jf_zK-ZLDsg-COlAh-aDfipJyKdgvH6RbZLOMc545i8fHLfyd6EsMGY1oyL19kO5QUlFa92sz_HWoOK5gYshICcRl_9HToD6AZj10jaDp0G1cNoFFp5s16DR-fO2IgWbpx8yjHOImNR7AGdDHOEOaAf0JkU0uu5jAZsDOjWxB6dOZtfTqCMTmpLd4u-SPUrMcZ-QkfoIhVzo_kNHbrsnY_5CvyIFqkPo-SwrS6Ht9krLYcA-w9xL7v6drxafM-XP09OF0fLXLGCxLwqW0kqLUktO1LWguGyA5CiE7qqtShE2xKiMJEgoSxp3dVKK8pFW2PGWo7pXvb5Xnea2xE6lTx4OTSTN6P0d42Tpvn_x5q-WbubRpSciYolgQ8PAt5dzxBiM5qgYBikBTeHpqiKssBphEVC3z9DN272NtnbUqxgVY1pog7vKeVdCB70YzMEN9tdaJ7tQsp499TDI_9v-PQvGx-zmA</recordid><startdate>20220930</startdate><enddate>20220930</enddate><creator>Álvarez, Sara Delgado</creator><creator>Velázquez Saornil, Jorge</creator><creator>Sánchez Milá, Zacarías</creator><creator>Jaén Crespo, Gonzalo</creator><creator>Campón Chekroun, Angélica</creator><creator>Barragán Casas, José Manuel</creator><creator>Frutos Llanes, Raúl</creator><creator>Rodríguez Sanz, David</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3629-6590</orcidid><orcidid>https://orcid.org/0000-0002-4129-2084</orcidid><orcidid>https://orcid.org/0000-0003-2608-2019</orcidid></search><sort><creationdate>20220930</creationdate><title>Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial</title><author>Álvarez, Sara Delgado ; Velázquez Saornil, Jorge ; Sánchez Milá, Zacarías ; Jaén Crespo, Gonzalo ; Campón Chekroun, Angélica ; Barragán Casas, José Manuel ; Frutos Llanes, Raúl ; Rodríguez Sanz, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-75ba17fa18ad1589405deea9d9f78f929bb11c01aeae5538d8cfc369b8044b603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Back pain</topic><topic>Clinical trials</topic><topic>Compression</topic><topic>Dry Needling</topic><topic>Humans</topic><topic>Hyperalgesia</topic><topic>Informed consent</topic><topic>Low back pain</topic><topic>Low Back Pain - therapy</topic><topic>Manipulative therapy</topic><topic>Muscles</topic><topic>Nervous system</topic><topic>Pain</topic><topic>Pain perception</topic><topic>Pathology</topic><topic>Patients</topic><topic>Quality assessment</topic><topic>Quality of Life</topic><topic>Range of motion</topic><topic>Statistical analysis</topic><topic>Therapeutic applications</topic><topic>Trigger Points</topic><topic>Uridine Diphosphate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Álvarez, Sara Delgado</creatorcontrib><creatorcontrib>Velázquez Saornil, Jorge</creatorcontrib><creatorcontrib>Sánchez Milá, Zacarías</creatorcontrib><creatorcontrib>Jaén Crespo, Gonzalo</creatorcontrib><creatorcontrib>Campón Chekroun, Angélica</creatorcontrib><creatorcontrib>Barragán Casas, José Manuel</creatorcontrib><creatorcontrib>Frutos Llanes, Raúl</creatorcontrib><creatorcontrib>Rodríguez Sanz, David</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Álvarez, Sara Delgado</au><au>Velázquez Saornil, Jorge</au><au>Sánchez Milá, Zacarías</au><au>Jaén Crespo, Gonzalo</au><au>Campón Chekroun, Angélica</au><au>Barragán Casas, José Manuel</au><au>Frutos Llanes, Raúl</au><au>Rodríguez Sanz, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2022-09-30</date><risdate>2022</risdate><volume>19</volume><issue>19</issue><spage>12468</spage><pages>12468-</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>The presence of latent myofascial trigger points (MTrPs) in the gluteus medius is one of the possible causes of non-specific low back pain. Dry needling (DN) and ischemic compression (IC) techniques may be useful for the treatment of these MTrPs.
For this study, 80 participants were randomly divided into two groups: the dry needling group, who received a single session of DN to the gluteus medius muscle plus hyperalgesia (
= 40), and the IC group, who received a single session of IC to the gluteus medius muscle plus hyperalgesia (
= 40). Pain intensity, the pressure pain threshold (PPT), range of motion (ROM), and quality of life were assessed at baseline, immediately after treatment, after 48 h, and one week after treatment.
Statistically significant differences were shown between the two groups immediately after the intervention, showing a decrease in PPT (
< 0.05) in the DN group and an increase in PPT in the IC group. These values increased more and were better maintained at 48 h and after one week of treatment in the DN group than in the IC group. Quality of life improved in both groups, with greater improvement in the DN group than in the IC group.
IC could be more advisable than DN with respect to UDP and pain intensity in the most hyperalgesic latent MTrPs of the gluteus medius muscle in subjects with non-specific low back pain, immediately after treatment. DN may be more effective than IC in terms of PPT, pain intensity, and quality of life in treating latent plus hyperalgesic gluteus medius muscle MTrPs in subjects with non-specific low back pain after 48 h and after one week of treatment.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36231767</pmid><doi>10.3390/ijerph191912468</doi><orcidid>https://orcid.org/0000-0002-3629-6590</orcidid><orcidid>https://orcid.org/0000-0002-4129-2084</orcidid><orcidid>https://orcid.org/0000-0003-2608-2019</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1660-4601 |
ispartof | International journal of environmental research and public health, 2022-09, Vol.19 (19), p.12468 |
issn | 1660-4601 1661-7827 1660-4601 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9564974 |
source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | Back pain Clinical trials Compression Dry Needling Humans Hyperalgesia Informed consent Low back pain Low Back Pain - therapy Manipulative therapy Muscles Nervous system Pain Pain perception Pathology Patients Quality assessment Quality of Life Range of motion Statistical analysis Therapeutic applications Trigger Points Uridine Diphosphate |
title | Effectiveness of Dry Needling and Ischemic Trigger Point Compression in the Gluteus Medius in Patients with Non-Specific Low Back Pain: A Randomized Short-Term Clinical Trial |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T06%3A39%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effectiveness%20of%20Dry%20Needling%20and%20Ischemic%20Trigger%20Point%20Compression%20in%20the%20Gluteus%20Medius%20in%20Patients%20with%20Non-Specific%20Low%20Back%20Pain:%20A%20Randomized%20Short-Term%20Clinical%20Trial&rft.jtitle=International%20journal%20of%20environmental%20research%20and%20public%20health&rft.au=%C3%81lvarez,%20Sara%20Delgado&rft.date=2022-09-30&rft.volume=19&rft.issue=19&rft.spage=12468&rft.pages=12468-&rft.issn=1660-4601&rft.eissn=1660-4601&rft_id=info:doi/10.3390/ijerph191912468&rft_dat=%3Cproquest_pubme%3E2725203902%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2724247803&rft_id=info:pmid/36231767&rfr_iscdi=true |