Design, Synthesis, and Characterization of Stapled Oligosaccharides

Stapling short peptides to lock specific conformations and thereby obtain superior pharmacological properties is well established. However, similar concepts have not been applied to oligosaccharides. Here, we describe the design, synthesis, and characterization of the first stapled oligosaccharides....

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Veröffentlicht in:	Journal of the American Chemical Society 2022-10, Vol.144 (40), p.18429-18434
Hauptverfasser:	Ricardo, Manuel G., Reuber, Emelie E., Yao, Ling, Danglad-Flores, José, Delbianco, Martina, Seeberger, Peter H.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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