Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects an...
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| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2022-10, Vol.2022, p.1-11 |
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| creator | Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai |
| description | Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity. |
| doi_str_mv | 10.1155/2022/8011953 |
| format | Article |
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HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2022/8011953</identifier><language>eng</language><publisher>New York: Hindawi</publisher><subject>Acids ; Anemia ; Antioxidants ; Arsenic ; Batteries ; Cadmium ; Carcinogens ; DNA methylation ; Drinking water ; Enzymes ; Food chains ; Free radicals ; Gene expression ; Heavy metals ; Hemoglobin ; Lead content ; Lead poisoning ; Lipid peroxidation ; Lipids ; Manufacturing ; Medicinal plants ; Metallurgy ; Minerals ; Nervous system ; Nickel ; Oxidative stress ; Review ; Teratogenicity ; Therapeutic applications ; Toxicity</subject><ispartof>Evidence-based complementary and alternative medicine, 2022-10, Vol.2022, p.1-11</ispartof><rights>Copyright © 2022 Sukeerthi Dasharathy et al.</rights><rights>Copyright © 2022 Sukeerthi Dasharathy et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 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| source | Wiley Open Access; PubMed Central; Alma/SFX Local Collection; EZB Electronic Journals Library; PubMed Central Open Access |
| subjects | Acids Anemia Antioxidants Arsenic Batteries Cadmium Carcinogens DNA methylation Drinking water Enzymes Food chains Free radicals Gene expression Heavy metals Hemoglobin Lead content Lead poisoning Lipid peroxidation Lipids Manufacturing Medicinal plants Metallurgy Minerals Nervous system Nickel Oxidative stress Review Teratogenicity Therapeutic applications Toxicity |
| title | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
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