Macrophage immunomodulation accelerates skeletal muscle functional recovery in aged mice following disuse atrophy

Poor recovery of muscle size and strength with aging coincides with a dysregulated macrophage response during the early stages of regrowth. Immunomodulation in the form of ex vivo cytokine (macrophage-colony stimulating factor) or polarized macrophage delivery has been demonstrated to improve skelet...

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Veröffentlicht in:	Journal of applied physiology (1985) 2022-10, Vol.133 (4), p.919-931
Hauptverfasser:	Ferrara, Patrick J, Yee, Elena M, Petrocelli, Jonathan J, Fix, Dennis K, Hauser, Carson T, de Hart, Naomi M M P, Mahmassani, Ziad S, Reidy, Paul T, O'Connell, Ryan M, Drummond, Micah J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytokines Hindlimb Suspension - physiology Immunomodulation Macrophages - pathology Mice Muscle, Skeletal - physiology Muscular Atrophy Muscular Disorders, Atrophic - pathology
Online-Zugang:	Volltext
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