Meningeal lymphatics prime tumor immunity in glioblastoma

Meningeal lymphatics prime tumor immunity in glioblastoma

The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens....

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Veröffentlicht in:Cancer cell 2021-03, Vol.39 (3), p.304-306
Hauptverfasser: Graham, Maya S., Mellinghoff, Ingo K.
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description The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens. The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens.
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title Meningeal lymphatics prime tumor immunity in glioblastoma
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