Measuring RNA UNCG Tetraloop Refolding Dynamics Using Temperature-Jump/Drop Infrared Spectroscopy

Determining the structural dynamics of RNA and DNA is essential to understanding their cellular function, but direct measurement of strand association or folding remains experimentally challenging. Here we illustrate a temperature-jump/drop method able to reveal refolding dynamics. Time-resolved tem...

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Veröffentlicht in:	The journal of physical chemistry letters 2022-10, Vol.13 (39), p.9171-9176
Hauptverfasser:	Howe, C. P., Greetham, G. M., Procacci, B., Parker, A. W., Hunt, N. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter Physical Insights into the Biosphere, Atmosphere, and Space
Online-Zugang:	Volltext
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