Mucus-degrading Bacteroides link carbapenems to aggravated graft-versushost disease

The intestinal microbiota is an important modulator of graft-versus-host disease (GVHD), which often complicates allogeneic hematopoietic stem cell transplantation (allo-HSCT). Broadspectrum antibiotics such as carbapenems increase the risk for intestinal GVHD, but mechanisms are not well-understood...

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Veröffentlicht in:	Cell 2022-09, Vol.185 (20), p.3705-3719.e14
Hauptverfasser:	Hayase, Eiko, Hayase, Tomo, Jamal, Mohamed A., Miyama, Takahiko, Chang, Chia-Chi, Ortega, Miriam R., Ahmed, Saira S., Karmouch, Jennifer L., Sanchez, Christopher A., Brown, Alexandria N., El-Himri, Rawan K., Flores, Ivonne I., McDaniel, Lauren K., Pham, Dung, Halsey, Taylor, Frenk, Annette C., Chapa, Valerie A., Heckel, Brooke E., Jin, Yimei, Tsai, Wen-Bin, Prasad, Rishika, Tan, Lin, Veillon, Lucas, Ajami, Nadim J., Wargo, Jennifer A., Galloway-Peña, Jessica, Shelburne, Samuel, Chemaly, Roy F., Davey, Lauren, Glowacki, Robert W. P., Liu, Chen, Rondon, Gabriela, Alousi, Amin M., Molldrem, Jeffrey J., Champlin, Richard E., Shpall, Elizabeth J., Valdivia, Raphael H., Martens, Eric C., Lorenzi, Philip L., Jenq, Robert R.
Format:	Artikel
Sprache:	eng
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