Postoperative Acute Kidney Injury
Postoperative AKI is a common complication of major surgery and is associated with significant morbidity and mortality. The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine...
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Veröffentlicht in: | Clinical journal of the American Society of Nephrology 2022-10, Vol.17 (10), p.1535-1545 |
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creator | Boyer, Naomi Eldridge, Jack Prowle, John R Forni, Lui G |
description | Postoperative AKI is a common complication of major surgery and is associated with significant morbidity and mortality. The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine output. However, such conventional diagnostic criteria may be inaccurate in the postoperative period, suggesting a potential to refine diagnosis by application of novel diagnostic biomarkers. Risk factors for the development of postoperative AKI can be thought of in terms of preoperative, intraoperative, and postoperative factors and, as such, represent areas that may be targeted perioperatively to minimize the risk of AKI. The treatment of postoperative AKI remains predominantly supportive, although application of management bundles may translate into improved outcomes. |
doi_str_mv | 10.2215/CJN.16541221 |
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The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine output. However, such conventional diagnostic criteria may be inaccurate in the postoperative period, suggesting a potential to refine diagnosis by application of novel diagnostic biomarkers. Risk factors for the development of postoperative AKI can be thought of in terms of preoperative, intraoperative, and postoperative factors and, as such, represent areas that may be targeted perioperatively to minimize the risk of AKI. 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The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine output. However, such conventional diagnostic criteria may be inaccurate in the postoperative period, suggesting a potential to refine diagnosis by application of novel diagnostic biomarkers. Risk factors for the development of postoperative AKI can be thought of in terms of preoperative, intraoperative, and postoperative factors and, as such, represent areas that may be targeted perioperatively to minimize the risk of AKI. The treatment of postoperative AKI remains predominantly supportive, although application of management bundles may translate into improved outcomes.</description><subject>Acute Kidney Injury - diagnosis</subject><subject>Acute Kidney Injury - etiology</subject><subject>Acute Kidney Injury - therapy</subject><subject>Biomarkers</subject><subject>Creatinine</subject><subject>Critical Care Nephrology and Acute Kidney Injury</subject><subject>Humans</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - therapy</subject><subject>Risk Factors</subject><issn>1555-9041</issn><issn>1555-905X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkEFPwzAMhSMEYmNw44zGnY44aZL2gjRVAwYTcACJW5SmDnTa2iltJ_XfUxir4GRbfn7P-gg5BzphDMR18vA0ASlC6KYDMgQhRBBT8X7Y9yEMyElVLSkNQ87EMRlwoYAqUENy-VJWdblBb-p8i-OpbWocP-ZZge14Xiwb356SI2dWFZ791hF5u529JvfB4vlunkwXgWVSQoDUGSZTQJkK4aRJFU9NxJyLKfIsjJ1lmVNomaWcAhhhoohHKBV2z6MCPiI3O99Nk64xs1jU3qz0xudr41tdmlz_3xT5p_4otzoWLGI_Blc7A-vLqvLo-lug-huV7lDpPapOfvE3rxfv2fAvmhlkXQ</recordid><startdate>202210</startdate><enddate>202210</enddate><creator>Boyer, Naomi</creator><creator>Eldridge, Jack</creator><creator>Prowle, John R</creator><creator>Forni, Lui G</creator><general>American Society of Nephrology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5002-2721</orcidid><orcidid>https://orcid.org/0000-0002-0617-5309</orcidid></search><sort><creationdate>202210</creationdate><title>Postoperative Acute Kidney Injury</title><author>Boyer, Naomi ; Eldridge, Jack ; Prowle, John R ; Forni, Lui G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2661-e0fa26b1e6b55f6ab73ba82ff90e3d49fc2df7ec2c03011a5a8838e67e165e713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acute Kidney Injury - diagnosis</topic><topic>Acute Kidney Injury - etiology</topic><topic>Acute Kidney Injury - therapy</topic><topic>Biomarkers</topic><topic>Creatinine</topic><topic>Critical Care Nephrology and Acute Kidney Injury</topic><topic>Humans</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - therapy</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boyer, Naomi</creatorcontrib><creatorcontrib>Eldridge, Jack</creatorcontrib><creatorcontrib>Prowle, John R</creatorcontrib><creatorcontrib>Forni, Lui G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical journal of the American Society of Nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boyer, Naomi</au><au>Eldridge, Jack</au><au>Prowle, John R</au><au>Forni, Lui G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postoperative Acute Kidney Injury</atitle><jtitle>Clinical journal of the American Society of Nephrology</jtitle><addtitle>Clin J Am Soc Nephrol</addtitle><date>2022-10</date><risdate>2022</risdate><volume>17</volume><issue>10</issue><spage>1535</spage><epage>1545</epage><pages>1535-1545</pages><issn>1555-9041</issn><eissn>1555-905X</eissn><abstract>Postoperative AKI is a common complication of major surgery and is associated with significant morbidity and mortality. The Kidney Disease Improving Global Outcomes AKI definition allows consensus classification and identification of postoperative AKI through changes in serum creatinine and/or urine output. However, such conventional diagnostic criteria may be inaccurate in the postoperative period, suggesting a potential to refine diagnosis by application of novel diagnostic biomarkers. Risk factors for the development of postoperative AKI can be thought of in terms of preoperative, intraoperative, and postoperative factors and, as such, represent areas that may be targeted perioperatively to minimize the risk of AKI. 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subjects | Acute Kidney Injury - diagnosis Acute Kidney Injury - etiology Acute Kidney Injury - therapy Biomarkers Creatinine Critical Care Nephrology and Acute Kidney Injury Humans Postoperative Complications - diagnosis Postoperative Complications - etiology Postoperative Complications - therapy Risk Factors |
title | Postoperative Acute Kidney Injury |
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