Dcifer: an IBD-based method to calculate genetic distance between polyclonal infections

Abstract An essential step toward reconstructing pathogen transmission and answering epidemiologically relevant questions from genomic data is obtaining pairwise genetic distance between infections. For recombining organisms such as malaria parasites, relatedness measures quantifying recent shared a...

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Veröffentlicht in:	Genetics (Austin) 2022-09, Vol.222 (2)
Hauptverfasser:	Gerlovina, Inna, Gerlovin, Boris, Rodríguez-Barraquer, Isabel, Greenhouse, Bryan
Format:	Artikel
Sprache:	eng
Schlagworte:	Combinatorial analysis Complexity Epidemiology Gene frequency Genetic distance Genetics Geographical locations Haplotypes Infections Investigation Malaria Nucleotides Parasites Polymorphism Population genetics Single-nucleotide polymorphism Statistics Vector-borne diseases
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