Semisynthetic Glycoconjugate Vaccine Candidates against Escherichia coli O25B Induce Functional IgG Antibodies in Mice

Extraintestinal pathogenic Escherichia coli (ExPEC) is a major health concern due to emerging antibiotic resistance. Along with O1A, O2, and O6A, E. coli O25B is a major serotype within the ExPEC group, which expresses a unique O-antigen. Clinical studies with a glycoconjugate vaccine of the above-m...

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Veröffentlicht in:JACS Au 2022-09, Vol.2 (9), p.2135-2151
Hauptverfasser: Naini, Arun, Bartetzko, Max Peter, Sanapala, Someswara Rao, Broecker, Felix, Wirtz, Victoria, Lisboa, Marilda P., Parameswarappa, Sharavathi G., Knopp, Daniel, Przygodda, Jessica, Hakelberg, Matthias, Pan, Rosalind, Patel, Axay, Chorro, Laurent, Illenberger, Arthur, Ponce, Christopher, Kodali, Srinivas, Lypowy, Jacqueline, Anderson, Annaliesa S., Donald, Robert G. K., von Bonin, Arne, Pereira, Claney L.
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Sprache:eng
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