Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses

SARS-CoV-2 mRNA booster vaccines provide protection from severe disease, eliciting strong immunity that is further boosted by previous infection. However, it is unclear whether these immune responses are affected by the interval between infection and vaccination. Over a 2-month period, we evaluated...

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Veröffentlicht in:Cell 2022-11, Vol.185 (23), p.4333-4346.e14
Hauptverfasser: Buckner, Clarisa M., Kardava, Lela, El Merhebi, Omar, Narpala, Sandeep R., Serebryannyy, Leonid, Lin, Bob C., Wang, Wei, Zhang, Xiaozhen, Lopes de Assis, Felipe, Kelly, Sophie E.M., Teng, I-Ting, McCormack, Genevieve E., Praiss, Lauren H., Seamon, Catherine A., Rai, M. Ali, Kalish, Heather, Kwong, Peter D., Proschan, Michael A., McDermott, Adrian B., Fauci, Anthony S., Chun, Tae-Wook, Moir, Susan
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Sprache:eng
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