Basolateral Amygdala Hyperexcitability Is Associated with Precocious Developmental Emergence of Fear-Learning in Fragile X Syndrome

Fragile X Syndrome is a neurodevelopmental disorder and the most common monogenic cause of intellectual disability, autism spectrum disorders, and anxiety disorders. Loss of fragile x mental retardation protein results in disruptions of synaptic development during a critical period of circuit format...

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Veröffentlicht in:	The Journal of neuroscience 2022-09, Vol.42 (38), p.7294-7308
Hauptverfasser:	Svalina, Matthew N, Rio, Christian A Cea-Del, Kushner, J Keenan, Levy, Abigail, Baca, Serapio M, Guthman, E Mae, Opendak, Maya, Sullivan, Regina M, Restrepo, Diego, Huntsman, Molly M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Anxiety disorders Autism Circuits Critical period Disorders Fear FMR1 protein Fragile X syndrome Intellectual disabilities Learning Neurodevelopmental disorders Plasticity Synaptic plasticity Synaptogenesis
Online-Zugang:	Volltext
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