Prognostic Value, Immune Signature, and Molecular Mechanisms of the PHLDA Family in Pancreatic Adenocarcinoma

Increasing evidence supports the belief that the pleckstrin homology domain family A (PHLDA) family is associated with the development of a variety of cancers. However, the function of the PHLDA family members in PAAD is still unclear. Comprehensive bioinformatic analyses using R (version 3.6.3), Cy...

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Veröffentlicht in:	International journal of molecular sciences 2022-09, Vol.23 (18), p.10316
Hauptverfasser:	Duan, Yunjie, Du, Yongxing, Gu, Zongting, Zheng, Xiaohao, Wang, Chengfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - pathology Bioinformatics Biomarkers Biomarkers, Tumor - analysis Cancer therapies DNA methylation Drug development Gene Expression Regulation, Neoplastic Genes Homology Humans Immunoregulation Immunosuppressive agents MAP kinase Medical prognosis Molecular modelling Mutation Pancreatic cancer Pancreatic Neoplasms Pancreatic Neoplasms - pathology Pleckstrin Prognosis Proteins Therapeutic targets TOR protein TOR Serine-Threonine Kinases - metabolism Tumors
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