Obstructive Sleep Apnea and Role of the Diaphragm
Obstructive sleep apnea (OSA) causes multiple local and systemic pathophysiological consequences, which lead to an increase in morbidity and mortality in patients suffering from this disorder. OSA presents with various nocturnal events of apnoeas or hypopneas and with sub-clinical airflow limitation...
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Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2022-09, Vol.14 (9), p.e29004-e29004 |
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description | Obstructive sleep apnea (OSA) causes multiple local and systemic pathophysiological consequences, which lead to an increase in morbidity and mortality in patients suffering from this disorder. OSA presents with various nocturnal events of apnoeas or hypopneas and with sub-clinical airflow limitations during wakefulness. OSA involves a large percentage of the population, particularly men, but the estimate of OSA patients could be much broader than data from the literature. Most of the research carried out in the muscle field is to understand the causes of the presence of chronic nocturnal desaturation and focus on the genioglossus muscle and other muscles related to dilating the upper airways. Sparse research has been published regarding the diaphragm muscle, which is the main muscle structure to insufflate air into the airways. The article reviews the functional anatomy of the muscles used to open the upper respiratory tract and the non-physiological adaptation that follows in the presence of OSA, as well as the functional anatomy and pathological adaptive aspects of the diaphragm muscle. The intent of the text is to highlight the disparity of clinical interest between the dilator muscles and the diaphragm, trying to stimulate a broader approach to patient evaluation. |
doi_str_mv | 10.7759/cureus.29004 |
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OSA presents with various nocturnal events of apnoeas or hypopneas and with sub-clinical airflow limitations during wakefulness. OSA involves a large percentage of the population, particularly men, but the estimate of OSA patients could be much broader than data from the literature. Most of the research carried out in the muscle field is to understand the causes of the presence of chronic nocturnal desaturation and focus on the genioglossus muscle and other muscles related to dilating the upper airways. Sparse research has been published regarding the diaphragm muscle, which is the main muscle structure to insufflate air into the airways. The article reviews the functional anatomy of the muscles used to open the upper respiratory tract and the non-physiological adaptation that follows in the presence of OSA, as well as the functional anatomy and pathological adaptive aspects of the diaphragm muscle. 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The intent of the text is to highlight the disparity of clinical interest between the dilator muscles and the diaphragm, trying to stimulate a broader approach to patient evaluation.</description><subject>Anatomy</subject><subject>Asthma</subject><subject>Body mass index</subject><subject>Diabetes</subject><subject>Diaphragm (Anatomy)</subject><subject>Disease</subject><subject>Gastroesophageal reflux</subject><subject>Hypertension</subject><subject>Hypoxia</subject><subject>Metabolic syndrome</subject><subject>Mortality</subject><subject>Obesity</subject><subject>Osteopathic Medicine</subject><subject>Physical Medicine & Rehabilitation</subject><subject>Physiology</subject><subject>Respiration</subject><subject>Sleep apnea</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkU1LAzEQhoMoWLQ3f8CCFw-2JtlsPi5CqZ9QKPhxDkl2tt2yu1mT3YL_3q0top5mYB7emeFB6ILgqRCZunF9gD5OqcKYHaERJVxOJJHs-Fd_isYxbjDGBAuKBR4hsrSxC73ryi0krxVAm8zaBkximjx58RUkvki6NSR3pWnXwazqc3RSmCrC-FDP0PvD_dv8abJYPj7PZ4uJS4nqJkQUvBCkoJhZk7IcG0UsM1QyVwgMKeO5sFzlaWodwSCws4pyKw3HklNB0jN0u89te1tD7qDpgql0G8rahE_tTan_TppyrVd-qxVTGZV8CLg6BAT_0UPsdF1GB1VlGvB91MOSgZIZVwN6-Q_d-D40w3s7SnHOsmxHXe8pF3yMAYqfYwjWOwd670B_O0i_AFZZeb4</recordid><startdate>20220910</startdate><enddate>20220910</enddate><creator>Bordoni, Bruno</creator><creator>Escher, Allan R</creator><creator>Toccafondi, Anastasia</creator><creator>Mapelli, Luca</creator><creator>Banfi, Paolo</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220910</creationdate><title>Obstructive Sleep Apnea and Role of the Diaphragm</title><author>Bordoni, Bruno ; Escher, Allan R ; Toccafondi, Anastasia ; Mapelli, Luca ; Banfi, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-17f6f71f204ba34d0a91b4a284cf70e346d7b69d33bc10e70cb926b8a60862713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anatomy</topic><topic>Asthma</topic><topic>Body mass index</topic><topic>Diabetes</topic><topic>Diaphragm (Anatomy)</topic><topic>Disease</topic><topic>Gastroesophageal reflux</topic><topic>Hypertension</topic><topic>Hypoxia</topic><topic>Metabolic syndrome</topic><topic>Mortality</topic><topic>Obesity</topic><topic>Osteopathic Medicine</topic><topic>Physical Medicine & Rehabilitation</topic><topic>Physiology</topic><topic>Respiration</topic><topic>Sleep apnea</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bordoni, Bruno</creatorcontrib><creatorcontrib>Escher, Allan R</creatorcontrib><creatorcontrib>Toccafondi, Anastasia</creatorcontrib><creatorcontrib>Mapelli, Luca</creatorcontrib><creatorcontrib>Banfi, Paolo</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bordoni, Bruno</au><au>Escher, Allan R</au><au>Toccafondi, Anastasia</au><au>Mapelli, Luca</au><au>Banfi, Paolo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Obstructive Sleep Apnea and Role of the Diaphragm</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2022-09-10</date><risdate>2022</risdate><volume>14</volume><issue>9</issue><spage>e29004</spage><epage>e29004</epage><pages>e29004-e29004</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Obstructive sleep apnea (OSA) causes multiple local and systemic pathophysiological consequences, which lead to an increase in morbidity and mortality in patients suffering from this disorder. OSA presents with various nocturnal events of apnoeas or hypopneas and with sub-clinical airflow limitations during wakefulness. OSA involves a large percentage of the population, particularly men, but the estimate of OSA patients could be much broader than data from the literature. Most of the research carried out in the muscle field is to understand the causes of the presence of chronic nocturnal desaturation and focus on the genioglossus muscle and other muscles related to dilating the upper airways. Sparse research has been published regarding the diaphragm muscle, which is the main muscle structure to insufflate air into the airways. The article reviews the functional anatomy of the muscles used to open the upper respiratory tract and the non-physiological adaptation that follows in the presence of OSA, as well as the functional anatomy and pathological adaptive aspects of the diaphragm muscle. The intent of the text is to highlight the disparity of clinical interest between the dilator muscles and the diaphragm, trying to stimulate a broader approach to patient evaluation.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><doi>10.7759/cureus.29004</doi><oa>free_for_read</oa></addata></record> |
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subjects | Anatomy Asthma Body mass index Diabetes Diaphragm (Anatomy) Disease Gastroesophageal reflux Hypertension Hypoxia Metabolic syndrome Mortality Obesity Osteopathic Medicine Physical Medicine & Rehabilitation Physiology Respiration Sleep apnea |
title | Obstructive Sleep Apnea and Role of the Diaphragm |
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