Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study
Introduction Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait. Methods Data on d...
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Veröffentlicht in: | International urology and nephrology 2023-03, Vol.55 (3), p.721-727 |
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creator | AlSahow, Ali AlQallaf, Ahmed AlYousef, Anas Bahbahani, Hamad Bahbahani, Yousif AlHelal, Bassam AlRajab, Heba AlMuhaiteeb, Abdullah Shalaby, Heba Elabbadi, Mohamed Elsebaei, Mohammad Abdallah, Emad Ayoub, Medhat AbouTrabeh, Aissar AlSarrajji, Maryam AlAwadhi, Abdullah Kumar, Rajeev |
description | Introduction
Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait.
Methods
Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed.
Results
A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died.
Conclusion
HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality. |
doi_str_mv | 10.1007/s11255-022-03368-1 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9493158</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2716943437</sourcerecordid><originalsourceid>FETCH-LOGICAL-c425t-d1bd79115fd0d77ad7bfde024505d0e174fbb053ecccc1b55716c745c7c6443d3</originalsourceid><addsrcrecordid>eNp9kUtv1DAUhS1ERUvhD7BAltiwaMq9fsSTDVI1vEaq1A2wtRzbaV1l4mAng-bf45kppWVRy5KvdD6f6-tDyBuEcwRQHzIik7ICxirgvF5U-IycoFS8YnIhnj-oj8nLnG8BoFkAvCDHvEZesxpOiFutR2MnGju6vPq5-lRhQ8PQeTuFONCypxtPXTD9NodMxzjOvdlLY4p53GEbf0Zjm33a7AXTn9FhX_0OztM8zW77ihx1ps_-9d15Sn58-fx9-a26vPq6Wl5cVlYwOVUOW6caRNk5cEoZp9rOeWBCgnTgUYmubUFyb8vCVkqFtVVCWmVrIbjjp-TjwXec27V31g9TMr0eU1ibtNXRBP1YGcKNvo4b3YiGo1wUg_d3Bin-mn2e9Dpk6_veDD7OWbPSsRFccFXQd_-ht3FOZfwdpRoFKJqdITtQtnxXTr67fwyC3oWoDyHqEqLeh6ixXHr7cIz7K39TKwA_ALlIw7VP_3o_YfsHU2ypJg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2779701498</pqid></control><display><type>article</type><title>Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>AlSahow, Ali ; AlQallaf, Ahmed ; AlYousef, Anas ; Bahbahani, Hamad ; Bahbahani, Yousif ; AlHelal, Bassam ; AlRajab, Heba ; AlMuhaiteeb, Abdullah ; Shalaby, Heba ; Elabbadi, Mohamed ; Elsebaei, Mohammad ; Abdallah, Emad ; Ayoub, Medhat ; AbouTrabeh, Aissar ; AlSarrajji, Maryam ; AlAwadhi, Abdullah ; Kumar, Rajeev</creator><creatorcontrib>AlSahow, Ali ; AlQallaf, Ahmed ; AlYousef, Anas ; Bahbahani, Hamad ; Bahbahani, Yousif ; AlHelal, Bassam ; AlRajab, Heba ; AlMuhaiteeb, Abdullah ; Shalaby, Heba ; Elabbadi, Mohamed ; Elsebaei, Mohammad ; Abdallah, Emad ; Ayoub, Medhat ; AbouTrabeh, Aissar ; AlSarrajji, Maryam ; AlAwadhi, Abdullah ; Kumar, Rajeev</creatorcontrib><description>Introduction
Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait.
Methods
Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed.
Results
A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died.
Conclusion
HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.</description><identifier>ISSN: 1573-2584</identifier><identifier>ISSN: 0301-1623</identifier><identifier>EISSN: 1573-2584</identifier><identifier>DOI: 10.1007/s11255-022-03368-1</identifier><identifier>PMID: 36136260</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Aged ; Comorbidity ; Coronaviruses ; COVID-19 ; COVID-19 - complications ; Female ; Hemodialysis ; Hospitalization ; Humans ; Infections ; Kidney Failure, Chronic - therapy ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Mortality ; Nephrology ; Nephrology - Original Paper ; Population ; Population studies ; Prospective Studies ; Renal Dialysis - adverse effects ; Statistical analysis ; Urology</subject><ispartof>International urology and nephrology, 2023-03, Vol.55 (3), p.721-727</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c425t-d1bd79115fd0d77ad7bfde024505d0e174fbb053ecccc1b55716c745c7c6443d3</cites><orcidid>0000-0001-8081-3244</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11255-022-03368-1$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11255-022-03368-1$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36136260$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AlSahow, Ali</creatorcontrib><creatorcontrib>AlQallaf, Ahmed</creatorcontrib><creatorcontrib>AlYousef, Anas</creatorcontrib><creatorcontrib>Bahbahani, Hamad</creatorcontrib><creatorcontrib>Bahbahani, Yousif</creatorcontrib><creatorcontrib>AlHelal, Bassam</creatorcontrib><creatorcontrib>AlRajab, Heba</creatorcontrib><creatorcontrib>AlMuhaiteeb, Abdullah</creatorcontrib><creatorcontrib>Shalaby, Heba</creatorcontrib><creatorcontrib>Elabbadi, Mohamed</creatorcontrib><creatorcontrib>Elsebaei, Mohammad</creatorcontrib><creatorcontrib>Abdallah, Emad</creatorcontrib><creatorcontrib>Ayoub, Medhat</creatorcontrib><creatorcontrib>AbouTrabeh, Aissar</creatorcontrib><creatorcontrib>AlSarrajji, Maryam</creatorcontrib><creatorcontrib>AlAwadhi, Abdullah</creatorcontrib><creatorcontrib>Kumar, Rajeev</creatorcontrib><title>Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study</title><title>International urology and nephrology</title><addtitle>Int Urol Nephrol</addtitle><addtitle>Int Urol Nephrol</addtitle><description>Introduction
Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait.
Methods
Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed.
Results
A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died.
Conclusion
HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.</description><subject>Adult</subject><subject>Aged</subject><subject>Comorbidity</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - complications</subject><subject>Female</subject><subject>Hemodialysis</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Infections</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Nephrology</subject><subject>Nephrology - Original Paper</subject><subject>Population</subject><subject>Population studies</subject><subject>Prospective Studies</subject><subject>Renal Dialysis - adverse effects</subject><subject>Statistical analysis</subject><subject>Urology</subject><issn>1573-2584</issn><issn>0301-1623</issn><issn>1573-2584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kUtv1DAUhS1ERUvhD7BAltiwaMq9fsSTDVI1vEaq1A2wtRzbaV1l4mAng-bf45kppWVRy5KvdD6f6-tDyBuEcwRQHzIik7ICxirgvF5U-IycoFS8YnIhnj-oj8nLnG8BoFkAvCDHvEZesxpOiFutR2MnGju6vPq5-lRhQ8PQeTuFONCypxtPXTD9NodMxzjOvdlLY4p53GEbf0Zjm33a7AXTn9FhX_0OztM8zW77ihx1ps_-9d15Sn58-fx9-a26vPq6Wl5cVlYwOVUOW6caRNk5cEoZp9rOeWBCgnTgUYmubUFyb8vCVkqFtVVCWmVrIbjjp-TjwXec27V31g9TMr0eU1ibtNXRBP1YGcKNvo4b3YiGo1wUg_d3Bin-mn2e9Dpk6_veDD7OWbPSsRFccFXQd_-ht3FOZfwdpRoFKJqdITtQtnxXTr67fwyC3oWoDyHqEqLeh6ixXHr7cIz7K39TKwA_ALlIw7VP_3o_YfsHU2ypJg</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>AlSahow, Ali</creator><creator>AlQallaf, Ahmed</creator><creator>AlYousef, Anas</creator><creator>Bahbahani, Hamad</creator><creator>Bahbahani, Yousif</creator><creator>AlHelal, Bassam</creator><creator>AlRajab, Heba</creator><creator>AlMuhaiteeb, Abdullah</creator><creator>Shalaby, Heba</creator><creator>Elabbadi, Mohamed</creator><creator>Elsebaei, Mohammad</creator><creator>Abdallah, Emad</creator><creator>Ayoub, Medhat</creator><creator>AbouTrabeh, Aissar</creator><creator>AlSarrajji, Maryam</creator><creator>AlAwadhi, Abdullah</creator><creator>Kumar, Rajeev</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8081-3244</orcidid></search><sort><creationdate>20230301</creationdate><title>Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study</title><author>AlSahow, Ali ; AlQallaf, Ahmed ; AlYousef, Anas ; Bahbahani, Hamad ; Bahbahani, Yousif ; AlHelal, Bassam ; AlRajab, Heba ; AlMuhaiteeb, Abdullah ; Shalaby, Heba ; Elabbadi, Mohamed ; Elsebaei, Mohammad ; Abdallah, Emad ; Ayoub, Medhat ; AbouTrabeh, Aissar ; AlSarrajji, Maryam ; AlAwadhi, Abdullah ; Kumar, Rajeev</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c425t-d1bd79115fd0d77ad7bfde024505d0e174fbb053ecccc1b55716c745c7c6443d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Comorbidity</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 - complications</topic><topic>Female</topic><topic>Hemodialysis</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Infections</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Nephrology</topic><topic>Nephrology - Original Paper</topic><topic>Population</topic><topic>Population studies</topic><topic>Prospective Studies</topic><topic>Renal Dialysis - adverse effects</topic><topic>Statistical analysis</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AlSahow, Ali</creatorcontrib><creatorcontrib>AlQallaf, Ahmed</creatorcontrib><creatorcontrib>AlYousef, Anas</creatorcontrib><creatorcontrib>Bahbahani, Hamad</creatorcontrib><creatorcontrib>Bahbahani, Yousif</creatorcontrib><creatorcontrib>AlHelal, Bassam</creatorcontrib><creatorcontrib>AlRajab, Heba</creatorcontrib><creatorcontrib>AlMuhaiteeb, Abdullah</creatorcontrib><creatorcontrib>Shalaby, Heba</creatorcontrib><creatorcontrib>Elabbadi, Mohamed</creatorcontrib><creatorcontrib>Elsebaei, Mohammad</creatorcontrib><creatorcontrib>Abdallah, Emad</creatorcontrib><creatorcontrib>Ayoub, Medhat</creatorcontrib><creatorcontrib>AbouTrabeh, Aissar</creatorcontrib><creatorcontrib>AlSarrajji, Maryam</creatorcontrib><creatorcontrib>AlAwadhi, Abdullah</creatorcontrib><creatorcontrib>Kumar, Rajeev</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AlSahow, Ali</au><au>AlQallaf, Ahmed</au><au>AlYousef, Anas</au><au>Bahbahani, Hamad</au><au>Bahbahani, Yousif</au><au>AlHelal, Bassam</au><au>AlRajab, Heba</au><au>AlMuhaiteeb, Abdullah</au><au>Shalaby, Heba</au><au>Elabbadi, Mohamed</au><au>Elsebaei, Mohammad</au><au>Abdallah, Emad</au><au>Ayoub, Medhat</au><au>AbouTrabeh, Aissar</au><au>AlSarrajji, Maryam</au><au>AlAwadhi, Abdullah</au><au>Kumar, Rajeev</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study</atitle><jtitle>International urology and nephrology</jtitle><stitle>Int Urol Nephrol</stitle><addtitle>Int Urol Nephrol</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>55</volume><issue>3</issue><spage>721</spage><epage>727</epage><pages>721-727</pages><issn>1573-2584</issn><issn>0301-1623</issn><eissn>1573-2584</eissn><abstract>Introduction
Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait.
Methods
Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed.
Results
A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died.
Conclusion
HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>36136260</pmid><doi>10.1007/s11255-022-03368-1</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-8081-3244</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Comorbidity Coronaviruses COVID-19 COVID-19 - complications Female Hemodialysis Hospitalization Humans Infections Kidney Failure, Chronic - therapy Male Medicine Medicine & Public Health Middle Aged Mortality Nephrology Nephrology - Original Paper Population Population studies Prospective Studies Renal Dialysis - adverse effects Statistical analysis Urology |
title | Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study |
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