Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study

Introduction Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait. Methods Data on d...

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Veröffentlicht in:International urology and nephrology 2023-03, Vol.55 (3), p.721-727
Hauptverfasser: AlSahow, Ali, AlQallaf, Ahmed, AlYousef, Anas, Bahbahani, Hamad, Bahbahani, Yousif, AlHelal, Bassam, AlRajab, Heba, AlMuhaiteeb, Abdullah, Shalaby, Heba, Elabbadi, Mohamed, Elsebaei, Mohammad, Abdallah, Emad, Ayoub, Medhat, AbouTrabeh, Aissar, AlSarrajji, Maryam, AlAwadhi, Abdullah, Kumar, Rajeev
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container_issue 3
container_start_page 721
container_title International urology and nephrology
container_volume 55
creator AlSahow, Ali
AlQallaf, Ahmed
AlYousef, Anas
Bahbahani, Hamad
Bahbahani, Yousif
AlHelal, Bassam
AlRajab, Heba
AlMuhaiteeb, Abdullah
Shalaby, Heba
Elabbadi, Mohamed
Elsebaei, Mohammad
Abdallah, Emad
Ayoub, Medhat
AbouTrabeh, Aissar
AlSarrajji, Maryam
AlAwadhi, Abdullah
Kumar, Rajeev
description Introduction Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait. Methods Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed. Results A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died. Conclusion HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.
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Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait. Methods Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed. Results A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died. Conclusion HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.</description><identifier>ISSN: 1573-2584</identifier><identifier>ISSN: 0301-1623</identifier><identifier>EISSN: 1573-2584</identifier><identifier>DOI: 10.1007/s11255-022-03368-1</identifier><identifier>PMID: 36136260</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Aged ; Comorbidity ; Coronaviruses ; COVID-19 ; COVID-19 - complications ; Female ; Hemodialysis ; Hospitalization ; Humans ; Infections ; Kidney Failure, Chronic - therapy ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Mortality ; Nephrology ; Nephrology - Original Paper ; Population ; Population studies ; Prospective Studies ; Renal Dialysis - adverse effects ; Statistical analysis ; Urology</subject><ispartof>International urology and nephrology, 2023-03, Vol.55 (3), p.721-727</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c425t-d1bd79115fd0d77ad7bfde024505d0e174fbb053ecccc1b55716c745c7c6443d3</cites><orcidid>0000-0001-8081-3244</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11255-022-03368-1$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11255-022-03368-1$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36136260$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AlSahow, Ali</creatorcontrib><creatorcontrib>AlQallaf, Ahmed</creatorcontrib><creatorcontrib>AlYousef, Anas</creatorcontrib><creatorcontrib>Bahbahani, Hamad</creatorcontrib><creatorcontrib>Bahbahani, Yousif</creatorcontrib><creatorcontrib>AlHelal, Bassam</creatorcontrib><creatorcontrib>AlRajab, Heba</creatorcontrib><creatorcontrib>AlMuhaiteeb, Abdullah</creatorcontrib><creatorcontrib>Shalaby, Heba</creatorcontrib><creatorcontrib>Elabbadi, Mohamed</creatorcontrib><creatorcontrib>Elsebaei, Mohammad</creatorcontrib><creatorcontrib>Abdallah, Emad</creatorcontrib><creatorcontrib>Ayoub, Medhat</creatorcontrib><creatorcontrib>AbouTrabeh, Aissar</creatorcontrib><creatorcontrib>AlSarrajji, Maryam</creatorcontrib><creatorcontrib>AlAwadhi, Abdullah</creatorcontrib><creatorcontrib>Kumar, Rajeev</creatorcontrib><title>Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study</title><title>International urology and nephrology</title><addtitle>Int Urol Nephrol</addtitle><addtitle>Int Urol Nephrol</addtitle><description>Introduction Hemodialysis (HD) patients are at increased risk of severe COVID-19 infection but infection rates vary. 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Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died. 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Our objectives are to describe COVID-19 positive HD patients’ characteristics, infection rates, and factors associated with mortality in HD COVID-19 cases in Kuwait. Methods Data on demographics, comorbidities, and treatments received, as well as mortality for HD patients admitted to hospitals for COVID-19, from 1/March to 31/July 2020, prospectively collected and analyzed. Results A total of 141 infected HD patients were admitted (Mean age 58 ± 16.1; Males 56%), representing 7% of the total HD population and 0.2% of all COVID-19 cases during the study period. Of those 141 infected HD patients, 27 (19%) died, and this represents 6% of total COVID-19-related mortality and 27% of the total HD mortality. In contrast, total covid-19-related mortality of all positive cases was only 0.7%, and total HD mortality during the study period was only 5%. COVID-19-positive HD patients who died were older and 59% were males. However, the differences were not statistically significant. Of the 61 infected HD patients who needed to be switched to continuous kidney replacement therapy (CKRT), 34% died, and of the 29 infected HD patients who needed admission to intensive care, 65% died. Conclusion HD population represents a small fraction of the total population; however, positive HD COVID-19 cases represent a sizable proportion of COVID-19 cases and a significant percentage of total COVID-19-related mortality, and total HD mortality.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>36136260</pmid><doi>10.1007/s11255-022-03368-1</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-8081-3244</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Adult
Aged
Comorbidity
Coronaviruses
COVID-19
COVID-19 - complications
Female
Hemodialysis
Hospitalization
Humans
Infections
Kidney Failure, Chronic - therapy
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Nephrology
Nephrology - Original Paper
Population
Population studies
Prospective Studies
Renal Dialysis - adverse effects
Statistical analysis
Urology
title Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study
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