Langerhans Cell Histiocytosis of the Mandible

The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a relia...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2022-08, Vol.14 (8)
Hauptverfasser: Padmanaban, Kamalakannan, Kamalakaran, Arunkumar, Raghavan, Priyadharshini, Palani, Triveni, Rajiah, Davidson
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container_title Curēus (Palo Alto, CA)
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creator Padmanaban, Kamalakannan
Kamalakaran, Arunkumar
Raghavan, Priyadharshini
Palani, Triveni
Rajiah, Davidson
description The unusual disorder known as Langerhans cell histiocytosis, which is most frequently seen in children and young adults, is caused by the clonal proliferation of Langerhans cells. Even if clinical signs and radiographic evidence of destructive bone lesions may raise suspicion of the disease, a reliable diagnosis without a thorough pathological examination is challenging. This report describes a case of eosinophilic granuloma of the mandible in a nine-year-old child with characteristic radiological, histopathological, and immunohistochemical features.
doi_str_mv 10.7759/cureus.28222
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subjects Antigens
Autoimmune diseases
Biopsy
Bone marrow
Case reports
Dendritic cells
Dentistry
Diabetes
Edema
Granulomas
Jaw
Lymphatic system
Other
Pathology
Rare diseases
Skin
Teeth
Tomography
title Langerhans Cell Histiocytosis of the Mandible
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