Effects of Coronary Artery Disease–Associated Variants on Vascular Smooth Muscle Cells

Genome-wide association studies have identified many genetic loci that are robustly associated with coronary artery disease (CAD). However, the underlying biological mechanisms are still unknown for most of these loci, hindering the progress to medical translation. Evidence suggests that the genetic...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2022-09, Vol.146 (12), p.917-929
Hauptverfasser:	Solomon, Charles U., McVey, David G., Andreadi, Catherine, Gong, Peng, Turner, Lenka, Stanczyk, Paulina J., Khemiri, Sonja, Chamberlain, Julie C., Yang, Wei, Webb, Tom R., Nelson, Christopher P., Samani, Nilesh J., Ye, Shu
Format:	Artikel
Sprache:	eng
Schlagworte:	Coronary Artery Disease - genetics Coronary Artery Disease - metabolism Genetic Predisposition to Disease Genome-Wide Association Study Humans Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - metabolism Original s Polymorphism, Single Nucleotide Quantitative Trait Loci
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!