XAF1 Protects Host against Emerging RNA Viruses by Stabilizing IRF1-Dependent Antiviral Immunity

XIAP-associated factor 1 (XAF1) is an interferon (IFN)-stimulated gene (ISG) that enhances IFN-induced apoptosis. However, it is unexplored whether XAF1 is essential for the host fighting against invaded viruses. Here, we find that XAF1 is significantly upregulated in the host cells infected with em...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of virology 2022-09, Vol.96 (17), p.e0077422-e0077422
Hauptverfasser:	Han, Yu, Bai, Xue, Liu, Siying, Zhu, Jingfei, Zhang, Fan, Xie, Lifen, Liu, Guodi, Jiang, Xiaohui, Zhang, Mingchao, Huang, Yingkang, Wang, Jingfeng, Li, Dapei, Zhang, Huiying, He, Yuanqing, He, Sudan, Xia, Yu, Xu, Xiulong, Xu, Feng, Ma, Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular Response to Infection Editor's Pick Immunology Spotlight Selection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!