Therapeutic Targeting of Cancer Stem Cells Prevents Resistance of Colorectal Cancer Cells to MEK Inhibition

Drug resistance is a leading cause for the failure of cancer treatments. Plasticity of cancer cells to acquire stem cell-like properties enables them to escape drug toxicity through different adaptive mechanisms. Eliminating cancer stem cells (CSCs) can potentially improve treatment outcomes for pat...

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Veröffentlicht in:	ACS pharmacology & translational science 2022-09, Vol.5 (9), p.724-734
Hauptverfasser:	Lamichhane, Astha, Shahi Thakuri, Pradip, Singh, Sunil, Rafsanjani Nejad, Pouria, Heiss, Jacob, Luker, Gary D., Tavana, Hossein
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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