PP1 phosphatases control PAR-2 localization and polarity establishment in C. elegans embryos

Cell polarity relies on the asymmetric distribution of the conserved PAR proteins, which is regulated by phosphorylation/dephosphorylation reactions. While the kinases involved have been well studied, the role of phosphatases remains poorly understood. In Caenorhabditis elegans zygotes, phosphorylat...

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Veröffentlicht in:	The Journal of cell biology 2022-10, Vol.221 (10), p.1
Hauptverfasser:	Calvi, Ida, Schwager, Françoise, Gotta, Monica
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Cell Cycle and Division Cell Polarity Dephosphorylation Development Embryo, Nonmammalian - metabolism Embryos Genetics Kinases Localization Par-2 protein Phosphatase Phosphoric Monoester Hydrolases - metabolism Phosphorylation Polarity Protein kinase C Protein Kinase C - metabolism Proteins Skewed distributions Zygotes
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