Neoadjuvant Chemotherapy and Nodal Response Rates in Luminal Breast Cancer: Effects of Age and Tumor Ki67

Background Neoadjuvant chemotherapy (NAC) is standard for most triple-negative and human epidermal growth factor receptor 2 (HER2)+ breast cancers, and frequently downstages node-positive (cN+) disease, permitting omission of axillary dissection. In estrogen receptor (ER)+/HER2– disease, response ra...

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Veröffentlicht in:	Annals of surgical oncology 2022-09, Vol.29 (9), p.5747-5756
Hauptverfasser:	Boughey, Judy C., Hoskin, Tanya L., Goetz, Matthew P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antineoplastic Combined Chemotherapy Protocols - therapeutic use Axilla - pathology Biopsy Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - surgery Breast Oncology Chemotherapy Chemotherapy, Adjuvant Decision making Epidermal growth factor ErbB-2 protein Estrogen receptors Female Humans Ki-67 Antigen Medicine Medicine & Public Health Middle Aged Neoadjuvant Therapy Oncology Patients Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Response rates Surgery Surgical Oncology Tumors
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