The DEAD-box helicase Hlc regulates basal transcription and chromatin opening of stress-responsive genes

Abstract Stress-responsive genes are lowly transcribed under normal conditions and robustly induced in response to stress. The significant difference between basal and induced transcription indicates that the general transcriptional machinery requires a mechanism to distinguish each transcription st...

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Veröffentlicht in:	Nucleic acids research 2022-09, Vol.50 (16), p.9175-9189
Hauptverfasser:	Jia, Ruirui, Lin, Jiamei, You, Jin, Li, Shi, Shan, Ge, Huang, Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatin - genetics DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism DNA Helicases - genetics DNA Helicases - metabolism Drosophila - genetics Gene Expression Regulation Gene regulation, Chromatin and Epigenetics RNA Polymerase II - genetics RNA Polymerase II - metabolism
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