Clinical Differences Between Elderly and Non-elderly Patients with COVID-19
Comorbidity frequency and mortality rates are higher in elderly patients with COVID-19. The disease is also more severe in elderly patients. This study aims to examine the characteristics of the COVID-19 disease, severity, comorbidities, and mortality rates in elderly patients by comparing them with...
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| Veröffentlicht in: | Turkish Thoracic Journal 2022-05, Vol.23 (3), p.238-245 |
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| creator | Demirci Üçsular, Fatma Karadeniz, Gülistan Polat, Gülru Ayrancı, Aysu Yalnız, Enver Kazankaya, Fatmanur Güldaval, Filiz Büyükşirin, Melih Anar, Ceyda |
| description | Comorbidity frequency and mortality rates are higher in elderly patients with COVID-19. The disease is also more severe in elderly patients. This study aims to examine the characteristics of the COVID-19 disease, severity, comorbidities, and mortality rates in elderly patients by comparing them with nonelderly patients.
This study was designed as a retrospective study. 469 patients who were followed up in outpatient, inpatient, and intensive care units with the diagnosis of COVID-19 between March 11, 2020, and June 01, 2020, were retrospectively included in the study. Patients were divided into two groups who were ≥65 years named as the "elderly group" and |
| doi_str_mv | 10.5152/TurkThoracJ.2022.21288 |
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This study was designed as a retrospective study. 469 patients who were followed up in outpatient, inpatient, and intensive care units with the diagnosis of COVID-19 between March 11, 2020, and June 01, 2020, were retrospectively included in the study. Patients were divided into two groups who were ≥65 years named as the "elderly group" and <65 years referred to as "nonelderly". Survival data was generated from the death notification system on August 02, 2020.
A total of 469 patients including elderly(n=101) and nonelderly(n=368) were included in the study retrospectively. The inci- dence of severe pneumonia(31%/12.6%) and critical illness(16%/5.8%), comorbidity (85%/37.2%) and hospitalization time(8/5 days) were significantly higher in the elderly group(p<0.05). 23 (22.8%) of elderly patients and 27(7.3%) of nonelderly patients died (p=0.000). Mortality was found to be 3.5 times higher than in the non-elderly group. The expected survival time was 145.85 days(CI 95%:133- 158.66) in the elderly patients and 170.36 days(CI 95%:166-174.6) in the nonelderly patients (p<0.000). In ROC analysis, the sensitivity of age was 86%(73.3-94.2), specificity was 66.83%(62.1-71.3), and the cut-off>56 (AUC:0.775; p <0.001) in predicting mortality.
Mortality is high, comorbidities are more frequent, and the disease is more severe in elderly patients with COVID-19. Age above 56 can be used as a cut-off to predict mortality.</description><identifier>ISSN: 1302-7808</identifier><identifier>ISSN: 2148-7197</identifier><identifier>EISSN: 2149-2530</identifier><identifier>DOI: 10.5152/TurkThoracJ.2022.21288</identifier><identifier>PMID: 35579231</identifier><language>eng</language><publisher>Turkey: AVES</publisher><subject>Age factors in disease ; Aged ; Analysis ; Health aspects ; Original ; Statistics</subject><ispartof>Turkish Thoracic Journal, 2022-05, Vol.23 (3), p.238-245</ispartof><rights>COPYRIGHT 2022 AVES</rights><rights>Turkish Thoracic Society 2022 Turkish Thoracic Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-3405c6a7a0351c2f6a29ea3623421d4b53ebff4f55a34e0e325ce5428a9b5e933</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450285/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450285/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35579231$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Demirci Üçsular, Fatma</creatorcontrib><creatorcontrib>Karadeniz, Gülistan</creatorcontrib><creatorcontrib>Polat, Gülru</creatorcontrib><creatorcontrib>Ayrancı, Aysu</creatorcontrib><creatorcontrib>Yalnız, Enver</creatorcontrib><creatorcontrib>Kazankaya, Fatmanur</creatorcontrib><creatorcontrib>Güldaval, Filiz</creatorcontrib><creatorcontrib>Büyükşirin, Melih</creatorcontrib><creatorcontrib>Anar, Ceyda</creatorcontrib><creatorcontrib>Department of Chest Diseases, Izmir Katip Celebi University Faculty of Medicine, Izmir, Turkey</creatorcontrib><creatorcontrib>Department of Chest Disease University of Health Sciencies, Dr Suat Seren Chest Disease and Surgery Training and Research Hospital, Izmir, Turkey</creatorcontrib><creatorcontrib>Department of Chest Diseases, Izmir Bakircay University Cigli Training and Research Hospital, Izmir, Turkey</creatorcontrib><title>Clinical Differences Between Elderly and Non-elderly Patients with COVID-19</title><title>Turkish Thoracic Journal</title><addtitle>Turk Thorac J</addtitle><description>Comorbidity frequency and mortality rates are higher in elderly patients with COVID-19. The disease is also more severe in elderly patients. This study aims to examine the characteristics of the COVID-19 disease, severity, comorbidities, and mortality rates in elderly patients by comparing them with nonelderly patients.
This study was designed as a retrospective study. 469 patients who were followed up in outpatient, inpatient, and intensive care units with the diagnosis of COVID-19 between March 11, 2020, and June 01, 2020, were retrospectively included in the study. Patients were divided into two groups who were ≥65 years named as the "elderly group" and <65 years referred to as "nonelderly". Survival data was generated from the death notification system on August 02, 2020.
A total of 469 patients including elderly(n=101) and nonelderly(n=368) were included in the study retrospectively. The inci- dence of severe pneumonia(31%/12.6%) and critical illness(16%/5.8%), comorbidity (85%/37.2%) and hospitalization time(8/5 days) were significantly higher in the elderly group(p<0.05). 23 (22.8%) of elderly patients and 27(7.3%) of nonelderly patients died (p=0.000). Mortality was found to be 3.5 times higher than in the non-elderly group. The expected survival time was 145.85 days(CI 95%:133- 158.66) in the elderly patients and 170.36 days(CI 95%:166-174.6) in the nonelderly patients (p<0.000). In ROC analysis, the sensitivity of age was 86%(73.3-94.2), specificity was 66.83%(62.1-71.3), and the cut-off>56 (AUC:0.775; p <0.001) in predicting mortality.
Mortality is high, comorbidities are more frequent, and the disease is more severe in elderly patients with COVID-19. Age above 56 can be used as a cut-off to predict mortality.</description><subject>Age factors in disease</subject><subject>Aged</subject><subject>Analysis</subject><subject>Health aspects</subject><subject>Original</subject><subject>Statistics</subject><issn>1302-7808</issn><issn>2148-7197</issn><issn>2149-2530</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNptkU9PGzEQxa2qVYkoXwGt1Esvm9oz9v65VKKBFgqCHtJeLcc7Jm43XrA3RXx7nCYgkLAP1njee5rRj7FDwadKKPg8X8e_8-UQjf0xBQ4wBQFN84ZNQMi2BIX8LZsI5FDWDW_22EFKf3g-iLyq8D3bQ6XqFlBM2Pms98Fb0xfH3jmKFCyl4iuNd0ShOOk7iv19YUJXXA6hpF3904yewpiKOz8ui9nV77PjUrQf2Dtn-kQHu3ef_fp2Mp-dlhdX389mRxellY0YS5Rc2crUhqMSFlxloCWDFaAE0cmFQlo4J51SBiVxQlCWlITGtAtFLeI--7LNvVkvVtTZPEk0vb6JfmXivR6M1y87wS_19fBPt1JxaFQO-LQLiMPtmtKoVz5Z6nsTaFgnDVWlVIXA2yz9uJVem560D27IiXYj10c1l4C1akRWTV9R5dvRytshkPP5_4Wh2hpsHFKK5J6mF1xvGOtnjPWGsf7POBsPn-_-ZHskig_bhqNR</recordid><startdate>20220501</startdate><enddate>20220501</enddate><creator>Demirci Üçsular, Fatma</creator><creator>Karadeniz, Gülistan</creator><creator>Polat, Gülru</creator><creator>Ayrancı, Aysu</creator><creator>Yalnız, Enver</creator><creator>Kazankaya, Fatmanur</creator><creator>Güldaval, Filiz</creator><creator>Büyükşirin, Melih</creator><creator>Anar, Ceyda</creator><general>AVES</general><general>Turkish Thoracic Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20220501</creationdate><title>Clinical Differences Between Elderly and Non-elderly Patients with COVID-19</title><author>Demirci Üçsular, Fatma ; Karadeniz, Gülistan ; Polat, Gülru ; Ayrancı, Aysu ; Yalnız, Enver ; Kazankaya, Fatmanur ; Güldaval, Filiz ; Büyükşirin, Melih ; Anar, Ceyda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-3405c6a7a0351c2f6a29ea3623421d4b53ebff4f55a34e0e325ce5428a9b5e933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Age factors in disease</topic><topic>Aged</topic><topic>Analysis</topic><topic>Health aspects</topic><topic>Original</topic><topic>Statistics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Demirci Üçsular, Fatma</creatorcontrib><creatorcontrib>Karadeniz, Gülistan</creatorcontrib><creatorcontrib>Polat, Gülru</creatorcontrib><creatorcontrib>Ayrancı, Aysu</creatorcontrib><creatorcontrib>Yalnız, Enver</creatorcontrib><creatorcontrib>Kazankaya, Fatmanur</creatorcontrib><creatorcontrib>Güldaval, Filiz</creatorcontrib><creatorcontrib>Büyükşirin, Melih</creatorcontrib><creatorcontrib>Anar, Ceyda</creatorcontrib><creatorcontrib>Department of Chest Diseases, Izmir Katip Celebi University Faculty of Medicine, Izmir, Turkey</creatorcontrib><creatorcontrib>Department of Chest Disease University of Health Sciencies, Dr Suat Seren Chest Disease and Surgery Training and Research Hospital, Izmir, Turkey</creatorcontrib><creatorcontrib>Department of Chest Diseases, Izmir Bakircay University Cigli Training and Research Hospital, Izmir, Turkey</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Turkish Thoracic Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Demirci Üçsular, Fatma</au><au>Karadeniz, Gülistan</au><au>Polat, Gülru</au><au>Ayrancı, Aysu</au><au>Yalnız, Enver</au><au>Kazankaya, Fatmanur</au><au>Güldaval, Filiz</au><au>Büyükşirin, Melih</au><au>Anar, Ceyda</au><aucorp>Department of Chest Diseases, Izmir Katip Celebi University Faculty of Medicine, Izmir, Turkey</aucorp><aucorp>Department of Chest Disease University of Health Sciencies, Dr Suat Seren Chest Disease and Surgery Training and Research Hospital, Izmir, Turkey</aucorp><aucorp>Department of Chest Diseases, Izmir Bakircay University Cigli Training and Research Hospital, Izmir, Turkey</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Differences Between Elderly and Non-elderly Patients with COVID-19</atitle><jtitle>Turkish Thoracic Journal</jtitle><addtitle>Turk Thorac J</addtitle><date>2022-05-01</date><risdate>2022</risdate><volume>23</volume><issue>3</issue><spage>238</spage><epage>245</epage><pages>238-245</pages><issn>1302-7808</issn><issn>2148-7197</issn><eissn>2149-2530</eissn><abstract>Comorbidity frequency and mortality rates are higher in elderly patients with COVID-19. The disease is also more severe in elderly patients. This study aims to examine the characteristics of the COVID-19 disease, severity, comorbidities, and mortality rates in elderly patients by comparing them with nonelderly patients.
This study was designed as a retrospective study. 469 patients who were followed up in outpatient, inpatient, and intensive care units with the diagnosis of COVID-19 between March 11, 2020, and June 01, 2020, were retrospectively included in the study. Patients were divided into two groups who were ≥65 years named as the "elderly group" and <65 years referred to as "nonelderly". Survival data was generated from the death notification system on August 02, 2020.
A total of 469 patients including elderly(n=101) and nonelderly(n=368) were included in the study retrospectively. The inci- dence of severe pneumonia(31%/12.6%) and critical illness(16%/5.8%), comorbidity (85%/37.2%) and hospitalization time(8/5 days) were significantly higher in the elderly group(p<0.05). 23 (22.8%) of elderly patients and 27(7.3%) of nonelderly patients died (p=0.000). Mortality was found to be 3.5 times higher than in the non-elderly group. The expected survival time was 145.85 days(CI 95%:133- 158.66) in the elderly patients and 170.36 days(CI 95%:166-174.6) in the nonelderly patients (p<0.000). In ROC analysis, the sensitivity of age was 86%(73.3-94.2), specificity was 66.83%(62.1-71.3), and the cut-off>56 (AUC:0.775; p <0.001) in predicting mortality.
Mortality is high, comorbidities are more frequent, and the disease is more severe in elderly patients with COVID-19. Age above 56 can be used as a cut-off to predict mortality.</abstract><cop>Turkey</cop><pub>AVES</pub><pmid>35579231</pmid><doi>10.5152/TurkThoracJ.2022.21288</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Age factors in disease Aged Analysis Health aspects Original Statistics |
| title | Clinical Differences Between Elderly and Non-elderly Patients with COVID-19 |
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