Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination

Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination

In this Perspective, we discuss what we perceive to be the continued challenges faced in catalytic hydrophosphination chemistry. Currently the literature is dominated by catalysts, many of which are highly effective, that generate the same phosphorus architectures, e.g., anti-Markovnikov products fr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS catalysis 2022-09, Vol.12 (17), p.10939-10949
Hauptverfasser: Lau, Samantha, Hood, Thomas M., Webster, Ruth L.
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 10949
container_issue 17
container_start_page 10939
container_title ACS catalysis
container_volume 12
creator Lau, Samantha
Hood, Thomas M.
Webster, Ruth L.
description In this Perspective, we discuss what we perceive to be the continued challenges faced in catalytic hydrophosphination chemistry. Currently the literature is dominated by catalysts, many of which are highly effective, that generate the same phosphorus architectures, e.g., anti-Markovnikov products from the reaction of activated alkenes and alkynes with diarylphosphines. We highlight the state of the art in stereoselective hydrophosphination and the scope and limitations of chemoselective hydrophosphination with primary phosphines and PH3. We also highlight the progress in the chemistry of the heavier homologues. In general, we have tried to emphasize what is missing from our hydrophosphination armament, with the aim of guiding future research targets.
doi_str_mv 10.1021/acscatal.2c03144
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9442583</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2712846516</sourcerecordid><originalsourceid>FETCH-LOGICAL-a410t-6641ce3292e3173996c2fa06032cb83f4e3dc90814172952f258f4c08a1417293</originalsourceid><addsrcrecordid>eNp1UctOwzAQtBCIVqV3jjlyIMXPPC4giCggVSpCcLZcx2lcUjvYCVL_HlcpCA7sZVc7szPSDgDnCM4QxOhKSC9FJ5oZlpAgSo_AGCPGYkYJO_41j8DU-w0MRVmSpfAUjEgCMwwZGYOXO2fflYmend1qr_xNtDRRV6uosKbTpldlVNSiaZRZKx_NhQwLbaJib7zrtIwed6WzbW19W2sjOm3NGTipROPV9NAn4G1-_1o8xovlw1Nxu4gFRbCLk4QiqQjOsSIoJXmeSFwJmECC5SojFVWklDnMEEUpzhmuMMsqKmEmhg2ZgOtBt-1XW1VKZTonGt46vRVux63Q_C9idM3X9pPnlAYtEgQuDgLOfvTKdzy8QKqmEUbZ3nOcIpzRhKEkUOFAlc5671T1Y4Mg36fBv9PghzTCyeVwEhC-sb0z4Rn_078AJDSMFg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2712846516</pqid></control><display><type>article</type><title>Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination</title><source>American Chemical Society Journals</source><creator>Lau, Samantha ; Hood, Thomas M. ; Webster, Ruth L.</creator><creatorcontrib>Lau, Samantha ; Hood, Thomas M. ; Webster, Ruth L.</creatorcontrib><description>In this Perspective, we discuss what we perceive to be the continued challenges faced in catalytic hydrophosphination chemistry. Currently the literature is dominated by catalysts, many of which are highly effective, that generate the same phosphorus architectures, e.g., anti-Markovnikov products from the reaction of activated alkenes and alkynes with diarylphosphines. We highlight the state of the art in stereoselective hydrophosphination and the scope and limitations of chemoselective hydrophosphination with primary phosphines and PH3. We also highlight the progress in the chemistry of the heavier homologues. In general, we have tried to emphasize what is missing from our hydrophosphination armament, with the aim of guiding future research targets.</description><identifier>ISSN: 2155-5435</identifier><identifier>EISSN: 2155-5435</identifier><identifier>DOI: 10.1021/acscatal.2c03144</identifier><identifier>PMID: 36082053</identifier><language>eng</language><publisher>American Chemical Society</publisher><ispartof>ACS catalysis, 2022-09, Vol.12 (17), p.10939-10949</ispartof><rights>2022 The Authors. Published by American Chemical Society</rights><rights>2022 The Authors. Published by American Chemical Society 2022 The Authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a410t-6641ce3292e3173996c2fa06032cb83f4e3dc90814172952f258f4c08a1417293</citedby><cites>FETCH-LOGICAL-a410t-6641ce3292e3173996c2fa06032cb83f4e3dc90814172952f258f4c08a1417293</cites><orcidid>0000-0003-2506-2753 ; 0000-0001-9936-117X ; 0000-0001-9199-7579</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acscatal.2c03144$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acscatal.2c03144$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,780,784,885,2765,27076,27924,27925,56738,56788</link.rule.ids></links><search><creatorcontrib>Lau, Samantha</creatorcontrib><creatorcontrib>Hood, Thomas M.</creatorcontrib><creatorcontrib>Webster, Ruth L.</creatorcontrib><title>Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination</title><title>ACS catalysis</title><addtitle>ACS Catal</addtitle><description>In this Perspective, we discuss what we perceive to be the continued challenges faced in catalytic hydrophosphination chemistry. Currently the literature is dominated by catalysts, many of which are highly effective, that generate the same phosphorus architectures, e.g., anti-Markovnikov products from the reaction of activated alkenes and alkynes with diarylphosphines. We highlight the state of the art in stereoselective hydrophosphination and the scope and limitations of chemoselective hydrophosphination with primary phosphines and PH3. We also highlight the progress in the chemistry of the heavier homologues. In general, we have tried to emphasize what is missing from our hydrophosphination armament, with the aim of guiding future research targets.</description><issn>2155-5435</issn><issn>2155-5435</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1UctOwzAQtBCIVqV3jjlyIMXPPC4giCggVSpCcLZcx2lcUjvYCVL_HlcpCA7sZVc7szPSDgDnCM4QxOhKSC9FJ5oZlpAgSo_AGCPGYkYJO_41j8DU-w0MRVmSpfAUjEgCMwwZGYOXO2fflYmend1qr_xNtDRRV6uosKbTpldlVNSiaZRZKx_NhQwLbaJib7zrtIwed6WzbW19W2sjOm3NGTipROPV9NAn4G1-_1o8xovlw1Nxu4gFRbCLk4QiqQjOsSIoJXmeSFwJmECC5SojFVWklDnMEEUpzhmuMMsqKmEmhg2ZgOtBt-1XW1VKZTonGt46vRVux63Q_C9idM3X9pPnlAYtEgQuDgLOfvTKdzy8QKqmEUbZ3nOcIpzRhKEkUOFAlc5671T1Y4Mg36fBv9PghzTCyeVwEhC-sb0z4Rn_078AJDSMFg</recordid><startdate>20220902</startdate><enddate>20220902</enddate><creator>Lau, Samantha</creator><creator>Hood, Thomas M.</creator><creator>Webster, Ruth L.</creator><general>American Chemical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2506-2753</orcidid><orcidid>https://orcid.org/0000-0001-9936-117X</orcidid><orcidid>https://orcid.org/0000-0001-9199-7579</orcidid></search><sort><creationdate>20220902</creationdate><title>Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination</title><author>Lau, Samantha ; Hood, Thomas M. ; Webster, Ruth L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a410t-6641ce3292e3173996c2fa06032cb83f4e3dc90814172952f258f4c08a1417293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lau, Samantha</creatorcontrib><creatorcontrib>Hood, Thomas M.</creatorcontrib><creatorcontrib>Webster, Ruth L.</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>ACS catalysis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lau, Samantha</au><au>Hood, Thomas M.</au><au>Webster, Ruth L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination</atitle><jtitle>ACS catalysis</jtitle><addtitle>ACS Catal</addtitle><date>2022-09-02</date><risdate>2022</risdate><volume>12</volume><issue>17</issue><spage>10939</spage><epage>10949</epage><pages>10939-10949</pages><issn>2155-5435</issn><eissn>2155-5435</eissn><abstract>In this Perspective, we discuss what we perceive to be the continued challenges faced in catalytic hydrophosphination chemistry. Currently the literature is dominated by catalysts, many of which are highly effective, that generate the same phosphorus architectures, e.g., anti-Markovnikov products from the reaction of activated alkenes and alkynes with diarylphosphines. We highlight the state of the art in stereoselective hydrophosphination and the scope and limitations of chemoselective hydrophosphination with primary phosphines and PH3. We also highlight the progress in the chemistry of the heavier homologues. In general, we have tried to emphasize what is missing from our hydrophosphination armament, with the aim of guiding future research targets.</abstract><pub>American Chemical Society</pub><pmid>36082053</pmid><doi>10.1021/acscatal.2c03144</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2506-2753</orcidid><orcidid>https://orcid.org/0000-0001-9936-117X</orcidid><orcidid>https://orcid.org/0000-0001-9199-7579</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2155-5435
ispartof ACS catalysis, 2022-09, Vol.12 (17), p.10939-10949
issn 2155-5435
2155-5435
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9442583
source American Chemical Society Journals
title Broken Promises? On the Continued Challenges Faced in Catalytic Hydrophosphination
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T03%3A49%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Broken%20Promises?%20On%20the%20Continued%20Challenges%20Faced%20in%20Catalytic%20Hydrophosphination&rft.jtitle=ACS%20catalysis&rft.au=Lau,%20Samantha&rft.date=2022-09-02&rft.volume=12&rft.issue=17&rft.spage=10939&rft.epage=10949&rft.pages=10939-10949&rft.issn=2155-5435&rft.eissn=2155-5435&rft_id=info:doi/10.1021/acscatal.2c03144&rft_dat=%3Cproquest_pubme%3E2712846516%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2712846516&rft_id=info:pmid/36082053&rfr_iscdi=true