Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide

Lysine acetylation is a reversible and dynamic post-translational modification that plays vital roles in regulating multiple cellular processes including aging. However, acetylome-wide analysis in the aging process remains poorly studied in mammalian tissues. Nicotinamide adenine dinucleotide (NAD+)...

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Veröffentlicht in:	Molecular & cellular proteomics 2022-09, Vol.21 (9), p.100276-100276, Article 100276
Hauptverfasser:	Li, Jingshu, Cao, Ye, Niu, Kongyan, Qiu, Jiaqian, Wang, Han, You, Yingnan, Li, Dean, Luo, Yu, Zhu, Zhengjiang, Zhang, Yaoyang, Liu, Nan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Animals Liver - metabolism Lysine - metabolism Mammals - metabolism Mice NAD - metabolism Nicotinamide Mononucleotide - metabolism Nicotinamide Mononucleotide - pharmacology Sirtuins - metabolism
Online-Zugang:	Volltext
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