Growth Hormone, Not IGF-1 Is the Key Longevity Regulator in Mammals

There are extraordinary examples of evolutionary conservation in biology, one of which is revealed in aging biology. A robust case in point are three interrelated endocrine systems that have been linked to longevity: the growth hormone (GH), insulin (INS), and insulin-like growth factor (IGF) pathwa...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2022-09, Vol.77 (9), p.1719-1723
1. Verfasser:	Brown-Borg, Holly M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Aging Animals Body fat Endocrine system Evolutionary conservation Growth Hormone Growth hormones Insulin Insulin-Like Growth Factor I Insulin-like growth factors Lipid metabolism Lipolysis Longevity Mammals Metabolism Pituitary Pituitary gland THE JOURNAL OF GERONTOLOGY: Biological Sciences
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