Antinociceptive and Analgesic Effects of (2 R,6 R)-Hydroxynorketamine

Commonly used pain therapeutics, such as opioid medications, exert dangerous side effects and lack effectiveness in treating some types of pain. Ketamine is also used to treat pain, but side effects limit its widespread use. (2 R,6 R)-hydroxynorketamine (HNK) is a ketamine metabolite that potentiall...

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Veröffentlicht in:	The Journal of pharmacology and experimental therapeutics 2022-09, Vol.382 (3), p.256-265
Hauptverfasser:	Yost, Jonathan G., Wulf, Hildegard A., Browne, Caroline A., Lucki, Irwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavioral Pharmacology
Online-Zugang:	Volltext
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