PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling

As the second most common primary intracranial neoplasms, about 40% of pituitary adenomas (PAs) exhibit aggressive behaviors and resulting in poor patient prognosis. The molecular mechanisms underlying the aggressive behaviors of PAs are not yet fully understood. Biochemical studies have reported th...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2022-08, Vol.14 (15), p.6066-6080
Hauptverfasser:	Liu, Jingdian, Wang, Junwen, Tian, Weidong, Xu, Yu, Li, Ran, Zhao, Kai, You, Chao, Zhu, Yuan, Bartsch, Joerg Walter, Niu, Hongquan, Zhang, Huaqiu, Shu, Kai, Lei, Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - genetics Apoptosis Regulatory Proteins - genetics Apoptosis Regulatory Proteins - metabolism Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Epithelial-Mesenchymal Transition - genetics Gene Expression Regulation, Neoplastic Humans MAP Kinase Signaling System Membrane Proteins - genetics Pituitary Neoplasms - genetics Pituitary Neoplasms - pathology Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-akt - metabolism Receptors, Interleukin-8B - metabolism Research Paper Signal Transduction
Online-Zugang:	Volltext
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