Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study

Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study

This study aimed to investigate the macrophage migration inhibitory factor (MIF) and associated clinical factors in neonates. Clinical information and blood samples were obtained from 77 neonates. Clinical details were reviewed from medical records, and MIF was measured by enzyme-linked immunosorben...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Medicine (Baltimore) 2022-08, Vol.101 (34), p.e30223-e30223
Hauptverfasser: Park, Ji Sook, Jun, Jin Su, Cho, Jae Young, Yeom, Jung Sook, Seo, Ji-Hyun, Lim, Jae Young, Park, Chan-Hoo, Woo, Hyang-Ok, Youn, Hee-Shang
Format: Artikel
Sprache:eng
Schlagworte:
Observational Study
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page e30223
container_issue 34
container_start_page e30223
container_title Medicine (Baltimore)
container_volume 101
creator Park, Ji Sook
Jun, Jin Su
Cho, Jae Young
Yeom, Jung Sook
Seo, Ji-Hyun
Lim, Jae Young
Park, Chan-Hoo
Woo, Hyang-Ok
Youn, Hee-Shang
description This study aimed to investigate the macrophage migration inhibitory factor (MIF) and associated clinical factors in neonates. Clinical information and blood samples were obtained from 77 neonates. Clinical details were reviewed from medical records, and MIF was measured by enzyme-linked immunosorbent assay using blood samples acquired within a week after birth. Statistical analyses were performed between plasma MIF concentration and clinical factors. Among the 77 newborn infants, 25 were born at
doi_str_mv 10.1097/MD.0000000000030223
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9410574</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2708733819</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4278-8e655a42a7df2353fa44dba37b2a3a0a8316b1a1b183eef88f5f6ce3c5705b5b3</originalsourceid><addsrcrecordid>eNpdkcmO1DAQhiMEYhZ4Ai4-csmM1zjhgISm2aQZwQHOVsUpdwyO09gJrXkFnhrT3WLzpUq___rKrqqqZ4xeMdrp67vNFf1zBOVcPKjOmRJNrbpGPvwrP6sucv5CKROay8fVmWio5KrrzqsfG-8cJowWiY9kApvm3QhbJJPfJlj8HIs--t4vc7onDmyJpMdljxjJLuGCaSIQB3JIIu77OcV8UCDn2frCiFtig4_eQjgR8gvyMWHwk49QsHlZh_sn1SMHIePTU7ysPr95_enmXX374e37m1e3tZVct3WLjVIgOejBcaGEAymHHoTuOQig0ArW9AxYz1qB6NrWKddYFFZpqnrVi8vq5ZG7W_sJB4txSRDMLvmpvMXM4M2_N9GPZjt_N51kVGlZAM9PgDR_WzEvZvLZYggQcV6z4Zq2WoiWdcUqjtYy1pwTut9tGDW_tmjuNub_LZYqeazaz6GMNX8N6x6TGRHCMh7sSne85sVMW97Quijltz8B_rqikA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2708733819</pqid></control><display><type>article</type><title>Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Wolters Kluwer Open Health</source><source>IngentaConnect Free/Open Access Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Park, Ji Sook ; Jun, Jin Su ; Cho, Jae Young ; Yeom, Jung Sook ; Seo, Ji-Hyun ; Lim, Jae Young ; Park, Chan-Hoo ; Woo, Hyang-Ok ; Youn, Hee-Shang</creator><creatorcontrib>Park, Ji Sook ; Jun, Jin Su ; Cho, Jae Young ; Yeom, Jung Sook ; Seo, Ji-Hyun ; Lim, Jae Young ; Park, Chan-Hoo ; Woo, Hyang-Ok ; Youn, Hee-Shang</creatorcontrib><description>This study aimed to investigate the macrophage migration inhibitory factor (MIF) and associated clinical factors in neonates. Clinical information and blood samples were obtained from 77 neonates. Clinical details were reviewed from medical records, and MIF was measured by enzyme-linked immunosorbent assay using blood samples acquired within a week after birth. Statistical analyses were performed between plasma MIF concentration and clinical factors. Among the 77 newborn infants, 25 were born at &lt;34 weeks of gestation (preterm), 25 at 34 to 37 weeks (late preterm), and 27 at term gestation. The mean MIF was 9849.5 ± 7187.8 pg/mL in preterm, 5718.7 ± 4596.4 in late preterm, and 5361.1 ± 3895.7 in term infants (P = .016). Among 25 preterm infants born at &lt;34 weeks of gestation, MIF was significantly higher in infants with necrotizing enterocolitis (NEC, 19,478.6 ± 8162.4 pg/mL, n = 5) than that in infants without NEC (feeding intolerance 7173.7 ± 4203.0 pg/mL, n = 12 and others 7844.9 ± 5311.2 pg/mL, n = 8, P = .020). Elevated plasma MIF levels in the transitional period were significantly associated with preterm birth before 34 weeks of gestation and the development of NEC.</description><identifier>ISSN: 1536-5964</identifier><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000030223</identifier><identifier>PMID: 36042599</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams &amp; Wilkins</publisher><subject>Observational Study</subject><ispartof>Medicine (Baltimore), 2022-08, Vol.101 (34), p.e30223-e30223</ispartof><rights>Lippincott Williams &amp; Wilkins</rights><rights>Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4278-8e655a42a7df2353fa44dba37b2a3a0a8316b1a1b183eef88f5f6ce3c5705b5b3</citedby><cites>FETCH-LOGICAL-c4278-8e655a42a7df2353fa44dba37b2a3a0a8316b1a1b183eef88f5f6ce3c5705b5b3</cites><orcidid>0000-0002-4704-2246</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410574/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410574/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Park, Ji Sook</creatorcontrib><creatorcontrib>Jun, Jin Su</creatorcontrib><creatorcontrib>Cho, Jae Young</creatorcontrib><creatorcontrib>Yeom, Jung Sook</creatorcontrib><creatorcontrib>Seo, Ji-Hyun</creatorcontrib><creatorcontrib>Lim, Jae Young</creatorcontrib><creatorcontrib>Park, Chan-Hoo</creatorcontrib><creatorcontrib>Woo, Hyang-Ok</creatorcontrib><creatorcontrib>Youn, Hee-Shang</creatorcontrib><title>Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study</title><title>Medicine (Baltimore)</title><description>This study aimed to investigate the macrophage migration inhibitory factor (MIF) and associated clinical factors in neonates. Clinical information and blood samples were obtained from 77 neonates. Clinical details were reviewed from medical records, and MIF was measured by enzyme-linked immunosorbent assay using blood samples acquired within a week after birth. Statistical analyses were performed between plasma MIF concentration and clinical factors. Among the 77 newborn infants, 25 were born at &lt;34 weeks of gestation (preterm), 25 at 34 to 37 weeks (late preterm), and 27 at term gestation. The mean MIF was 9849.5 ± 7187.8 pg/mL in preterm, 5718.7 ± 4596.4 in late preterm, and 5361.1 ± 3895.7 in term infants (P = .016). Among 25 preterm infants born at &lt;34 weeks of gestation, MIF was significantly higher in infants with necrotizing enterocolitis (NEC, 19,478.6 ± 8162.4 pg/mL, n = 5) than that in infants without NEC (feeding intolerance 7173.7 ± 4203.0 pg/mL, n = 12 and others 7844.9 ± 5311.2 pg/mL, n = 8, P = .020). Elevated plasma MIF levels in the transitional period were significantly associated with preterm birth before 34 weeks of gestation and the development of NEC.</description><subject>Observational Study</subject><issn>1536-5964</issn><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkcmO1DAQhiMEYhZ4Ai4-csmM1zjhgISm2aQZwQHOVsUpdwyO09gJrXkFnhrT3WLzpUq___rKrqqqZ4xeMdrp67vNFf1zBOVcPKjOmRJNrbpGPvwrP6sucv5CKROay8fVmWio5KrrzqsfG-8cJowWiY9kApvm3QhbJJPfJlj8HIs--t4vc7onDmyJpMdljxjJLuGCaSIQB3JIIu77OcV8UCDn2frCiFtig4_eQjgR8gvyMWHwk49QsHlZh_sn1SMHIePTU7ysPr95_enmXX374e37m1e3tZVct3WLjVIgOejBcaGEAymHHoTuOQig0ArW9AxYz1qB6NrWKddYFFZpqnrVi8vq5ZG7W_sJB4txSRDMLvmpvMXM4M2_N9GPZjt_N51kVGlZAM9PgDR_WzEvZvLZYggQcV6z4Zq2WoiWdcUqjtYy1pwTut9tGDW_tmjuNub_LZYqeazaz6GMNX8N6x6TGRHCMh7sSne85sVMW97Quijltz8B_rqikA</recordid><startdate>20220826</startdate><enddate>20220826</enddate><creator>Park, Ji Sook</creator><creator>Jun, Jin Su</creator><creator>Cho, Jae Young</creator><creator>Yeom, Jung Sook</creator><creator>Seo, Ji-Hyun</creator><creator>Lim, Jae Young</creator><creator>Park, Chan-Hoo</creator><creator>Woo, Hyang-Ok</creator><creator>Youn, Hee-Shang</creator><general>Lippincott Williams &amp; Wilkins</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4704-2246</orcidid></search><sort><creationdate>20220826</creationdate><title>Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study</title><author>Park, Ji Sook ; Jun, Jin Su ; Cho, Jae Young ; Yeom, Jung Sook ; Seo, Ji-Hyun ; Lim, Jae Young ; Park, Chan-Hoo ; Woo, Hyang-Ok ; Youn, Hee-Shang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4278-8e655a42a7df2353fa44dba37b2a3a0a8316b1a1b183eef88f5f6ce3c5705b5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Observational Study</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Ji Sook</creatorcontrib><creatorcontrib>Jun, Jin Su</creatorcontrib><creatorcontrib>Cho, Jae Young</creatorcontrib><creatorcontrib>Yeom, Jung Sook</creatorcontrib><creatorcontrib>Seo, Ji-Hyun</creatorcontrib><creatorcontrib>Lim, Jae Young</creatorcontrib><creatorcontrib>Park, Chan-Hoo</creatorcontrib><creatorcontrib>Woo, Hyang-Ok</creatorcontrib><creatorcontrib>Youn, Hee-Shang</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Ji Sook</au><au>Jun, Jin Su</au><au>Cho, Jae Young</au><au>Yeom, Jung Sook</au><au>Seo, Ji-Hyun</au><au>Lim, Jae Young</au><au>Park, Chan-Hoo</au><au>Woo, Hyang-Ok</au><au>Youn, Hee-Shang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study</atitle><jtitle>Medicine (Baltimore)</jtitle><date>2022-08-26</date><risdate>2022</risdate><volume>101</volume><issue>34</issue><spage>e30223</spage><epage>e30223</epage><pages>e30223-e30223</pages><issn>1536-5964</issn><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>This study aimed to investigate the macrophage migration inhibitory factor (MIF) and associated clinical factors in neonates. Clinical information and blood samples were obtained from 77 neonates. Clinical details were reviewed from medical records, and MIF was measured by enzyme-linked immunosorbent assay using blood samples acquired within a week after birth. Statistical analyses were performed between plasma MIF concentration and clinical factors. Among the 77 newborn infants, 25 were born at &lt;34 weeks of gestation (preterm), 25 at 34 to 37 weeks (late preterm), and 27 at term gestation. The mean MIF was 9849.5 ± 7187.8 pg/mL in preterm, 5718.7 ± 4596.4 in late preterm, and 5361.1 ± 3895.7 in term infants (P = .016). Among 25 preterm infants born at &lt;34 weeks of gestation, MIF was significantly higher in infants with necrotizing enterocolitis (NEC, 19,478.6 ± 8162.4 pg/mL, n = 5) than that in infants without NEC (feeding intolerance 7173.7 ± 4203.0 pg/mL, n = 12 and others 7844.9 ± 5311.2 pg/mL, n = 8, P = .020). Elevated plasma MIF levels in the transitional period were significantly associated with preterm birth before 34 weeks of gestation and the development of NEC.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams &amp; Wilkins</pub><pmid>36042599</pmid><doi>10.1097/MD.0000000000030223</doi><orcidid>https://orcid.org/0000-0002-4704-2246</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1536-5964
ispartof Medicine (Baltimore), 2022-08, Vol.101 (34), p.e30223-e30223
issn 1536-5964
0025-7974
1536-5964
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9410574
source DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wolters Kluwer Open Health; IngentaConnect Free/Open Access Journals; PubMed Central; Alma/SFX Local Collection
subjects Observational Study
title Difference in macrophage migration inhibitory factor between preterm and term newborns and associating clinical factors: Preliminary study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T02%3A42%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Difference%20in%20macrophage%20migration%20inhibitory%20factor%20between%20preterm%20and%20term%20newborns%20and%20associating%20clinical%20factors:%20Preliminary%20study&rft.jtitle=Medicine%20(Baltimore)&rft.au=Park,%20Ji%20Sook&rft.date=2022-08-26&rft.volume=101&rft.issue=34&rft.spage=e30223&rft.epage=e30223&rft.pages=e30223-e30223&rft.issn=1536-5964&rft.eissn=1536-5964&rft_id=info:doi/10.1097/MD.0000000000030223&rft_dat=%3Cproquest_pubme%3E2708733819%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2708733819&rft_id=info:pmid/36042599&rfr_iscdi=true