Tumor Necrosis Factor-α-Induced C-C Motif Chemokine Ligand 20 Expression through TNF Receptor 1-Dependent Activation of EGFR/p38 MAPK and JNK1/2/FoxO1 or the NF-κB Pathway in Human Cardiac Fibroblasts

Tumor necrosis factor (TNF)-α is involved in the pathogenesis of cardiac injury, inflammation, and apoptosis. It is a crucial pro-inflammatory cytokine in many heart disorders, including chronic heart failure and ischemic heart disease, contributing to cardiac remodeling and dysfunction. The implica...

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Veröffentlicht in:International journal of molecular sciences 2022-08, Vol.23 (16), p.9086
Hauptverfasser: Yang, Chuen-Mao, Yang, Chien-Chung, Hsu, Wun-Hsin, Hsiao, Li-Der, Tseng, Hui-Ching, Shih, Ya-Fang
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Sprache:eng
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