DNA Methyltransferases: From Evolution to Clinical Applications

DNA methylation is an epigenetic mark that living beings have used in different environments. The MTases family catalyzes DNA methylation. This process is conserved from archaea to eukaryotes, from fertilization to every stage of development, and from the early stages of cancer to metastasis. The fa...

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Veröffentlicht in:	International journal of molecular sciences 2022-08, Vol.23 (16), p.8994
Hauptverfasser:	Del Castillo Falconi, Victor M., Torres-Arciga, Karla, Matus-Ortega, Genaro, Díaz-Chávez, José, Herrera, Luis A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell cycle Cellular structure Chemical compounds Deregulation DNA methylation DNMT1 protein Epigenetics Eukaryotes Evolution Fertilization Gene expression Hepatitis Metabolites Metastases Metastasis Phenotypes Prokaryotes Review Structure-function relationships Target recognition Viruses
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