L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus

Abstract Besides the consequences of retrotransposition, long interspersed element 1 (L1) retrotransposons can affect the host genome through their antisense promoter. In addition to the sense promoter, the evolutionarily recent L1 retrotransposons, which are present in several thousand copies, also...

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Veröffentlicht in:	Human molecular genetics 2022-08, Vol.31 (15), p.2606-2622
Hauptverfasser:	Pinson, Marie-Elisa, Court, Franck, Masson, Aymeric, Renaud, Yoan, Fantini, Allison, Bacoeur-Ouzillou, Ophélie, Barriere, Marie, Pereira, Bruno, Guichet, Pierre-Olivier, Chautard, Emmanuel, Karayan-Tapon, Lucie, Verrelle, Pierre, Arnaud, Philippe, Vaurs-Barrière, Catherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Cancer Genomics Life Sciences Neurobiology Neurons and Cognition Original
Online-Zugang:	Volltext
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