Tenofovir-Diphosphate in Dried Blood Spots vs Tenofovir in Urine/Plasma for Oral Preexposure Prophylaxis Adherence Monitoring

Abstract Background Tenofovir-diphosphate (TFV-DP) measured in dried blood spots (DBS) and tenofovir (TFV) measured in urine/plasma have been used to measure TFV-based oral pre-exposure prophylaxis (PrEP) adherence. However, there are limited data comparing these 3 metrics and their appropriate use...

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Veröffentlicht in:	Open Forum Infectious Diseases 2022-08, Vol.9 (8), p.ofac405
Hauptverfasser:	Niu, Xin, Kubiak, Rachel W, Siriprakaisil, Oraphan, Klinbuyaem, Virat, Sukrakanchana, Pra ornsuda, Cressey, Ratchada, Okochi, Hideaki, Gandhi, Monica, Cressey, Tim R, Drain, Paul K
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Emtricitabine Liquid chromatography Major Mass spectrometry Patient compliance Tenofovir
Online-Zugang:	Volltext
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