Coexistence of Pancytopenia and Myositis After Developing COVID-19
COVID-19 causes not only acute but also subacute medical conditions during the clinical course. COVID-19 causes severe inflammatory conditions; therefore, patients may develop long-term complications. Among patients with acute COVID-19, some patients can experience persistent symptoms, such as fatig...
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creator | Okayasu, Tatsuhiko Ohta, Ryuichi Igarashi, Mari Kurita, Yasuo Hayakawa, Miho Sano, Chiaki |
description | COVID-19 causes not only acute but also subacute medical conditions during the clinical course. COVID-19 causes severe inflammatory conditions; therefore, patients may develop long-term complications. Among patients with acute COVID-19, some patients can experience persistent symptoms, such as fatigue, joint pain, and smell and taste abnormalities, known as the long COVID-19 syndrome. The symptoms can be severe and require continuous medical care. Patients with severe clinical courses of COVID-19 may have critical symptoms again after the cure of the acute infections, especially among older patients. We encountered a case of neutropenia and myositis one month after contracting COVID-19. An 89-year-old man presented to our hospital with acute-onset systemic muscle pain and difficulty in movement and speaking. The patient had neutropenia and myositis with an extremely high level of immunoglobulin G caused by COVID-19. A granulocyte colony-stimulating factor could be effective for treating neutropenia. Besides, prednisolone was effective for treating myositis. In community hospitals, after developing COVID-19, appropriate history taking and physical examination should be performed in older patients with ambiguous symptoms, as they might have critical medical conditions such as neutropenia and myositis. The appropriate diagnosis and treatments of older patients with the complications of COVID-19 should be performed. |
doi_str_mv | 10.7759/cureus.26978 |
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COVID-19 causes severe inflammatory conditions; therefore, patients may develop long-term complications. Among patients with acute COVID-19, some patients can experience persistent symptoms, such as fatigue, joint pain, and smell and taste abnormalities, known as the long COVID-19 syndrome. The symptoms can be severe and require continuous medical care. Patients with severe clinical courses of COVID-19 may have critical symptoms again after the cure of the acute infections, especially among older patients. We encountered a case of neutropenia and myositis one month after contracting COVID-19. An 89-year-old man presented to our hospital with acute-onset systemic muscle pain and difficulty in movement and speaking. The patient had neutropenia and myositis with an extremely high level of immunoglobulin G caused by COVID-19. A granulocyte colony-stimulating factor could be effective for treating neutropenia. Besides, prednisolone was effective for treating myositis. In community hospitals, after developing COVID-19, appropriate history taking and physical examination should be performed in older patients with ambiguous symptoms, as they might have critical medical conditions such as neutropenia and myositis. The appropriate diagnosis and treatments of older patients with the complications of COVID-19 should be performed.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.26978</identifier><identifier>PMID: 35989844</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Angina pectoris ; Antibodies ; Antigens ; Blood ; Bone marrow ; Case reports ; Coronaviruses ; COVID-19 ; Creatinine ; Emergency Medicine ; Family/General Practice ; Fractures ; Granulocytes ; Hemoglobin ; Hepatitis ; Hospitalization ; Immunoglobulins ; Infections ; Infectious Disease ; Inflammation ; Inflammatory diseases ; Long COVID ; Muscle pain ; Musculoskeletal diseases ; Neutropenia ; Neutrophils ; Patients ; Proteins ; Respiration ; Severe acute respiratory syndrome coronavirus 2</subject><ispartof>Curēus (Palo Alto, CA), 2022-07, Vol.14 (7)</ispartof><rights>Copyright © 2022, Okayasu et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Okayasu et al. 2022 Okayasu et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c286t-7c09cdff27859c5ff42da0528d567244c414c4218c069ef96453f0319f56ba503</citedby><cites>FETCH-LOGICAL-c286t-7c09cdff27859c5ff42da0528d567244c414c4218c069ef96453f0319f56ba503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385165/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385165/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids></links><search><creatorcontrib>Okayasu, Tatsuhiko</creatorcontrib><creatorcontrib>Ohta, Ryuichi</creatorcontrib><creatorcontrib>Igarashi, Mari</creatorcontrib><creatorcontrib>Kurita, Yasuo</creatorcontrib><creatorcontrib>Hayakawa, Miho</creatorcontrib><creatorcontrib>Sano, Chiaki</creatorcontrib><title>Coexistence of Pancytopenia and Myositis After Developing COVID-19</title><title>Curēus (Palo Alto, CA)</title><description>COVID-19 causes not only acute but also subacute medical conditions during the clinical course. COVID-19 causes severe inflammatory conditions; therefore, patients may develop long-term complications. Among patients with acute COVID-19, some patients can experience persistent symptoms, such as fatigue, joint pain, and smell and taste abnormalities, known as the long COVID-19 syndrome. The symptoms can be severe and require continuous medical care. Patients with severe clinical courses of COVID-19 may have critical symptoms again after the cure of the acute infections, especially among older patients. We encountered a case of neutropenia and myositis one month after contracting COVID-19. An 89-year-old man presented to our hospital with acute-onset systemic muscle pain and difficulty in movement and speaking. The patient had neutropenia and myositis with an extremely high level of immunoglobulin G caused by COVID-19. A granulocyte colony-stimulating factor could be effective for treating neutropenia. Besides, prednisolone was effective for treating myositis. In community hospitals, after developing COVID-19, appropriate history taking and physical examination should be performed in older patients with ambiguous symptoms, as they might have critical medical conditions such as neutropenia and myositis. The appropriate diagnosis and treatments of older patients with the complications of COVID-19 should be performed.</description><subject>Angina pectoris</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Blood</subject><subject>Bone marrow</subject><subject>Case reports</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Creatinine</subject><subject>Emergency Medicine</subject><subject>Family/General Practice</subject><subject>Fractures</subject><subject>Granulocytes</subject><subject>Hemoglobin</subject><subject>Hepatitis</subject><subject>Hospitalization</subject><subject>Immunoglobulins</subject><subject>Infections</subject><subject>Infectious Disease</subject><subject>Inflammation</subject><subject>Inflammatory diseases</subject><subject>Long COVID</subject><subject>Muscle pain</subject><subject>Musculoskeletal diseases</subject><subject>Neutropenia</subject><subject>Neutrophils</subject><subject>Patients</subject><subject>Proteins</subject><subject>Respiration</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpVkE1LAzEQhoMottTe_AELXt2aZPN5EWrrR6FSD-o1pNmkprSbNdkt9t-7WhE9DDMwL88MDwDnCI44p_LKtNG2aYSZ5OII9DFiIhdIkOM_cw8MU1pDCBHkGHJ4CnoFlUIKQvrgZhLsh0-NrYzNgsuedGX2Taht5XWmqzJ73IfkG5-ysWtszKZ2Zzeh9tUqmyxeZ9McyTNw4vQm2eFPH4CXu9vnyUM-X9zPJuN5brBgTc4NlKZ0DnNBpaHOEVxqSLEoKeOYEENQVxgJA5m0TjJCCwcLJB1lS01hMQDXB27dLre2NLZqot6oOvqtjnsVtFf_N5V_U6uwU7IQFDHaAS5-ADG8tzY1ah3aWHU_K8yhYJ0UwbvU5SFlYkgpWvd7AUH1JV0dpKtv6cUnATBzpQ</recordid><startdate>20220718</startdate><enddate>20220718</enddate><creator>Okayasu, Tatsuhiko</creator><creator>Ohta, Ryuichi</creator><creator>Igarashi, Mari</creator><creator>Kurita, Yasuo</creator><creator>Hayakawa, Miho</creator><creator>Sano, Chiaki</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20220718</creationdate><title>Coexistence of Pancytopenia and Myositis After Developing COVID-19</title><author>Okayasu, Tatsuhiko ; Ohta, Ryuichi ; Igarashi, Mari ; Kurita, Yasuo ; Hayakawa, Miho ; Sano, Chiaki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c286t-7c09cdff27859c5ff42da0528d567244c414c4218c069ef96453f0319f56ba503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Angina pectoris</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Blood</topic><topic>Bone marrow</topic><topic>Case reports</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Creatinine</topic><topic>Emergency Medicine</topic><topic>Family/General Practice</topic><topic>Fractures</topic><topic>Granulocytes</topic><topic>Hemoglobin</topic><topic>Hepatitis</topic><topic>Hospitalization</topic><topic>Immunoglobulins</topic><topic>Infections</topic><topic>Infectious Disease</topic><topic>Inflammation</topic><topic>Inflammatory diseases</topic><topic>Long COVID</topic><topic>Muscle pain</topic><topic>Musculoskeletal diseases</topic><topic>Neutropenia</topic><topic>Neutrophils</topic><topic>Patients</topic><topic>Proteins</topic><topic>Respiration</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okayasu, Tatsuhiko</creatorcontrib><creatorcontrib>Ohta, Ryuichi</creatorcontrib><creatorcontrib>Igarashi, Mari</creatorcontrib><creatorcontrib>Kurita, Yasuo</creatorcontrib><creatorcontrib>Hayakawa, Miho</creatorcontrib><creatorcontrib>Sano, Chiaki</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okayasu, Tatsuhiko</au><au>Ohta, Ryuichi</au><au>Igarashi, Mari</au><au>Kurita, Yasuo</au><au>Hayakawa, Miho</au><au>Sano, Chiaki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coexistence of Pancytopenia and Myositis After Developing COVID-19</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2022-07-18</date><risdate>2022</risdate><volume>14</volume><issue>7</issue><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>COVID-19 causes not only acute but also subacute medical conditions during the clinical course. COVID-19 causes severe inflammatory conditions; therefore, patients may develop long-term complications. Among patients with acute COVID-19, some patients can experience persistent symptoms, such as fatigue, joint pain, and smell and taste abnormalities, known as the long COVID-19 syndrome. The symptoms can be severe and require continuous medical care. Patients with severe clinical courses of COVID-19 may have critical symptoms again after the cure of the acute infections, especially among older patients. We encountered a case of neutropenia and myositis one month after contracting COVID-19. An 89-year-old man presented to our hospital with acute-onset systemic muscle pain and difficulty in movement and speaking. The patient had neutropenia and myositis with an extremely high level of immunoglobulin G caused by COVID-19. A granulocyte colony-stimulating factor could be effective for treating neutropenia. Besides, prednisolone was effective for treating myositis. In community hospitals, after developing COVID-19, appropriate history taking and physical examination should be performed in older patients with ambiguous symptoms, as they might have critical medical conditions such as neutropenia and myositis. The appropriate diagnosis and treatments of older patients with the complications of COVID-19 should be performed.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><pmid>35989844</pmid><doi>10.7759/cureus.26978</doi><oa>free_for_read</oa></addata></record> |
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subjects | Angina pectoris Antibodies Antigens Blood Bone marrow Case reports Coronaviruses COVID-19 Creatinine Emergency Medicine Family/General Practice Fractures Granulocytes Hemoglobin Hepatitis Hospitalization Immunoglobulins Infections Infectious Disease Inflammation Inflammatory diseases Long COVID Muscle pain Musculoskeletal diseases Neutropenia Neutrophils Patients Proteins Respiration Severe acute respiratory syndrome coronavirus 2 |
title | Coexistence of Pancytopenia and Myositis After Developing COVID-19 |
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