Effects of Zinc Glycinate on Growth Performance, Serum Biochemical Indexes, and Intestinal Morphology of Yellow Feather Broilers

The purpose of this study was to investigate the effects of zinc glycinate (Gly-Zn) on growth performance, serum biochemical index, intestinal morphology, and hepatic metallothionein (MT) mRNA expression in the liver of yellow feather broilers. A total of 540 18-day-old yellow feather broilers were...

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Veröffentlicht in:Biological trace element research 2022-09, Vol.200 (9), p.4089-4097
Hauptverfasser: Zhu, Xiaoping, Shang, Xiuguo, Lin, Guozhao, Li, Haojie, Feng, Xin, Zhang, Huihua
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Shang, Xiuguo
Lin, Guozhao
Li, Haojie
Feng, Xin
Zhang, Huihua
description The purpose of this study was to investigate the effects of zinc glycinate (Gly-Zn) on growth performance, serum biochemical index, intestinal morphology, and hepatic metallothionein (MT) mRNA expression in the liver of yellow feather broilers. A total of 540 18-day-old yellow feather broilers were randomly divided into three groups: control group (basal diet), ZnSO 4 group (basal diet plus 60 mg Zn/kg from ZnSO 4 ), and Gly-Zn group (basal diet plus 60 mg Zn/kg from zinc glycinate). Each treatment group had 6 replicates with 30 birds in each replicate. The experiment lasted for 42 days (18 to 59 days of age). The results showed that Gly-Zn supplementation significantly improved the average daily gain (ADG) and average daily feed intake (ADFI) of broilers during 18 to 39 days of age compared with that in the control group ( P  
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A total of 540 18-day-old yellow feather broilers were randomly divided into three groups: control group (basal diet), ZnSO 4 group (basal diet plus 60 mg Zn/kg from ZnSO 4 ), and Gly-Zn group (basal diet plus 60 mg Zn/kg from zinc glycinate). Each treatment group had 6 replicates with 30 birds in each replicate. The experiment lasted for 42 days (18 to 59 days of age). The results showed that Gly-Zn supplementation significantly improved the average daily gain (ADG) and average daily feed intake (ADFI) of broilers during 18 to 39 days of age compared with that in the control group ( P  &lt; 0.05) but not different from the ZnSO 4 group. The Gly-Zn group had higher glutathione peroxidase (GSH-Px) ( P  &lt; 0.05) and lower malondialdehyde (MDA) concentrations than the broilers in the control and ZnSO4 group. It was also observed that zinc content in the tibia of Gly-Zn group broilers was higher than the control and ZnSO4 group ( P  &lt; 0.05). The results of intestinal morphology parameters showed that the Gly-Zn group significantly increased the villus height in duodenum and jejunum ( P  &lt; 0.05) and decreased crypt depth in duodenum and ileum compared to the control group. However, there were no significant differences between the Gly-Zn group and ZnSO 4 group in duodenum and ileum regarding intestinal morphology parameters. The Gly-Zn group significantly increased mRNA expression of MT in the liver than both control and ZnSO 4 groups ( P  &lt; 0.05). Collectively, the results indicated that supplementing 60 mg Zn/kg through zinc glycinate improved growth performance and serum indexes as well as intestinal morphology of yellow feather broilers. It also regulates MT gene expression more effectively than the ZnSO 4 group at the transcriptional level.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>DOI: 10.1007/s12011-021-02990-x</identifier><identifier>PMID: 34739674</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Animal Feed - analysis ; Animals ; average daily gain ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; blood serum ; Chickens - metabolism ; Control ; Diet ; Diet - veterinary ; Dietary Supplements ; Duodenum ; Feathers ; feed intake ; Gene expression ; Glutathione ; Glutathione peroxidase ; Glycine - analogs &amp; derivatives ; Growth ; growth performance ; Ileum ; Intestine ; Intestines ; Jejunum ; Life Sciences ; Liver ; Malondialdehyde ; Metallothionein ; Metallothionein - genetics ; Metallothionein - metabolism ; Morphological indexes ; Morphology ; Nutrition ; Oncology ; Parameters ; Performance indices ; Peroxidase ; RNA, Messenger - metabolism ; Serum ; Small intestine ; Tibia ; transcription (genetics) ; villi ; Villus ; Zinc ; Zinc - metabolism ; Zinc sulfate</subject><ispartof>Biological trace element research, 2022-09, Vol.200 (9), p.4089-4097</ispartof><rights>The Author(s) 2021</rights><rights>2021. 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A total of 540 18-day-old yellow feather broilers were randomly divided into three groups: control group (basal diet), ZnSO 4 group (basal diet plus 60 mg Zn/kg from ZnSO 4 ), and Gly-Zn group (basal diet plus 60 mg Zn/kg from zinc glycinate). Each treatment group had 6 replicates with 30 birds in each replicate. The experiment lasted for 42 days (18 to 59 days of age). The results showed that Gly-Zn supplementation significantly improved the average daily gain (ADG) and average daily feed intake (ADFI) of broilers during 18 to 39 days of age compared with that in the control group ( P  &lt; 0.05) but not different from the ZnSO 4 group. The Gly-Zn group had higher glutathione peroxidase (GSH-Px) ( P  &lt; 0.05) and lower malondialdehyde (MDA) concentrations than the broilers in the control and ZnSO4 group. It was also observed that zinc content in the tibia of Gly-Zn group broilers was higher than the control and ZnSO4 group ( P  &lt; 0.05). 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A total of 540 18-day-old yellow feather broilers were randomly divided into three groups: control group (basal diet), ZnSO 4 group (basal diet plus 60 mg Zn/kg from ZnSO 4 ), and Gly-Zn group (basal diet plus 60 mg Zn/kg from zinc glycinate). Each treatment group had 6 replicates with 30 birds in each replicate. The experiment lasted for 42 days (18 to 59 days of age). The results showed that Gly-Zn supplementation significantly improved the average daily gain (ADG) and average daily feed intake (ADFI) of broilers during 18 to 39 days of age compared with that in the control group ( P  &lt; 0.05) but not different from the ZnSO 4 group. The Gly-Zn group had higher glutathione peroxidase (GSH-Px) ( P  &lt; 0.05) and lower malondialdehyde (MDA) concentrations than the broilers in the control and ZnSO4 group. It was also observed that zinc content in the tibia of Gly-Zn group broilers was higher than the control and ZnSO4 group ( P  &lt; 0.05). The results of intestinal morphology parameters showed that the Gly-Zn group significantly increased the villus height in duodenum and jejunum ( P  &lt; 0.05) and decreased crypt depth in duodenum and ileum compared to the control group. However, there were no significant differences between the Gly-Zn group and ZnSO 4 group in duodenum and ileum regarding intestinal morphology parameters. The Gly-Zn group significantly increased mRNA expression of MT in the liver than both control and ZnSO 4 groups ( P  &lt; 0.05). Collectively, the results indicated that supplementing 60 mg Zn/kg through zinc glycinate improved growth performance and serum indexes as well as intestinal morphology of yellow feather broilers. It also regulates MT gene expression more effectively than the ZnSO 4 group at the transcriptional level.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>34739674</pmid><doi>10.1007/s12011-021-02990-x</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-7785-3720</orcidid><oa>free_for_read</oa></addata></record>
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source MEDLINE; SpringerLink Journals
subjects Animal Feed - analysis
Animals
average daily gain
Biochemistry
Biomedical and Life Sciences
Biotechnology
blood serum
Chickens - metabolism
Control
Diet
Diet - veterinary
Dietary Supplements
Duodenum
Feathers
feed intake
Gene expression
Glutathione
Glutathione peroxidase
Glycine - analogs & derivatives
Growth
growth performance
Ileum
Intestine
Intestines
Jejunum
Life Sciences
Liver
Malondialdehyde
Metallothionein
Metallothionein - genetics
Metallothionein - metabolism
Morphological indexes
Morphology
Nutrition
Oncology
Parameters
Performance indices
Peroxidase
RNA, Messenger - metabolism
Serum
Small intestine
Tibia
transcription (genetics)
villi
Villus
Zinc
Zinc - metabolism
Zinc sulfate
title Effects of Zinc Glycinate on Growth Performance, Serum Biochemical Indexes, and Intestinal Morphology of Yellow Feather Broilers
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