Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action

The orbitofrontal cortex (OFC) and its major downstream target within the basal ganglia-the rostromedial caudate nucleus (rmCD)-are involved in reward-value processing and goal-directed behavior. However, a causal contribution of the pathway linking these two structures to goal-directed behavior has...

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Veröffentlicht in:The Journal of neuroscience 2022-08, Vol.42 (32), p.6267-6275
Hauptverfasser: Oyama, Kei, Hori, Yukiko, Mimura, Koki, Nagai, Yuji, Eldridge, Mark A G, Saunders, Richard C, Miyakawa, Naohisa, Hirabayashi, Toshiyuki, Hori, Yuki, Inoue, Ken-Ichi, Suhara, Tetsuya, Takada, Masahiko, Higuchi, Makoto, Richmond, Barry J, Minamimoto, Takafumi
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Sprache:eng
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